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Comment
. 2022 Feb;23(2):195-197.
doi: 10.1016/S1470-2045(21)00708-7.

Safety of adjuvant CDK4/6 inhibitors during the COVID-19 pandemic

Georg Pfeiler  1 , Angela DeMichele  2 , Amylou C Dueck  3 , Christian Fesl  4 , Michael Gnant  5 , Erica L Mayer  6
Affiliations
Comment

Safety of adjuvant CDK4/6 inhibitors during the COVID-19 pandemic

Georg Pfeiler et al. Lancet Oncol. 2022 Feb.
No abstract available

PubMed Disclaimer

Conflict of interest statement

GP reports personal fees from Novartis, Roche, AstraZeneca, Eli Lilly, and Amgen; and grants and personal fees from Pfizer, outside the submitted Comment. AD reports grants from the Alliance Foundation for Clinical Trials, during the conduct of the study; personal fees from Pfizer and Context Therapeutics; grants from Novartis, Pfizer, Genentech, Calithera, and Johnson and Johnson, outside the submitted Comment; and that their spouse is on a data safety monitoring board for a Pfizer drug not for use in oncology. CF reports grants from Pfizer, during the conduct of the study. MG reports personal fees from Amgen, Daiichi Sankyo, AstraZeneca, Eli Lilly, LifeBrain, Nanostring, Novartis, and TLC Biopharmaceuticals, all outside the submitted Comment; and that an immediate family member is employed by Sandoz. ELM reports personal fees from Eisai, Eli Lilly, and Novartis, outside the submitted work. ACD declares no competing interests. We received support from Alliance Foundation Trials, Austrian Breast and Colorectal Cancer Study Group, and the Breast International Group. The trial (including these analyses) was funded by Pfizer, who provided the study drug and financial support.

Comment on

  • Palbociclib with adjuvant endocrine therapy in early breast cancer (PALLAS): interim analysis of a multicentre, open-label, randomised, phase 3 study.
    Mayer EL, Dueck AC, Martin M, Rubovszky G, Burstein HJ, Bellet-Ezquerra M, Miller KD, Zdenkowski N, Winer EP, Pfeiler G, Goetz M, Ruiz-Borrego M, Anderson D, Nowecki Z, Loibl S, Moulder S, Ring A, Fitzal F, Traina T, Chan A, Rugo HS, Lemieux J, Henao F, Lyss A, Antolin Novoa S, Wolff AC, Vetter M, Egle D, Morris PG, Mamounas EP, Gil-Gil MJ, Prat A, Fohler H, Metzger Filho O, Schwarz M, DuFrane C, Fumagalli D, Theall KP, Lu DR, Bartlett CH, Koehler M, Fesl C, DeMichele A, Gnant M. Mayer EL, et al. Lancet Oncol. 2021 Feb;22(2):212-222. doi: 10.1016/S1470-2045(20)30642-2. Epub 2021 Jan 15. Lancet Oncol. 2021. PMID: 33460574 Clinical Trial.

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