Nirmatrelvir-ritonavir for COVID-19
- PMID: 35115376
- PMCID: PMC8900806
- DOI: 10.1503/cmaj.220081
Nirmatrelvir-ritonavir for COVID-19
Conflict of interest statement
Competing interests: Emily McDonald reports receiving salary support from the Fonds de Recherche Santé–Québec, and operating funds from the Canadian Institutes of Health Research (CIHR). Dr. McDonald also holds copyright in the software MedSafer. Todd Lee reports receiving research salary support from the Fonds de Recherche Santé–Québec, and operating funds from CIHR and the Interdisciplinary Initiative in Infection and Immunity (MI4). Dr. Lee also holds copyright in the software MedSafer.
Comment in
-
Benefits of nirmatrelvir-ritonavir remain unproven for some populations.CMAJ. 2022 Aug 2;194(29):E1041. doi: 10.1503/cmaj.146689-l. CMAJ. 2022. PMID: 35918091 Free PMC article. No abstract available.
Comment on
-
Renalism.CMAJ. 2022 Aug 2;194(29):E1040. doi: 10.1503/cmaj.146430-l. CMAJ. 2022. PMID: 35918093 Free PMC article. No abstract available.
References
-
- The COVID-19 Treatment Guidelines Panel’s statement on potential drug-drug interactions between ritonavir-boosted nirmatrelvir (Paxlovid) and concomitant medications. Bethesda (MD): National Institutes of Health; updated 2021 Dec. 30. Available: https://www.covid19treatmentguidelines.nih.gov/therapies/statement-on-pa... (accessed 2022 Jan. 16).
-
- Product monograph including patient medication information: Paxlovid. Kirkland (QC): Pfizer Canada ULC; 2022. Available: https://pdf.hres.ca/dpd_pm/00064313.PDF (accessed 2022 Jan. 23).
-
- Pfizer announces additional phase 2/3 study results confirming robust efficacy of novel COVID-19 oral antiviral treatment candidate in reducing risk of hospitalization or death. New York: Pfizer; 2021. Available: https://www.pfizer.com/news/press-release/press-release-detail/pfizer-an... (accessed 2022 Jan. 17).
-
- Fact sheet for healthcare providers: emergency use authorization for Paxlovid. Silver Spring (MD): US Food and Drug Administration; revised 2021 Dec. 22. Available: https://www.fda.gov/media/155050/download (accessed 2022 Jan. 16).
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources