The role of avelumab in advanced urothelial carcinoma in the context of a dynamic treatment landscape
- PMID: 35117082
- PMCID: PMC8797653
- DOI: 10.21037/tcr.2018.12.04
The role of avelumab in advanced urothelial carcinoma in the context of a dynamic treatment landscape
Conflict of interest statement
Conflicts of Interest: Dr. Grivas has done consulting with Pfizer, EMD Serono, Astra Zeneca, Merck & Co., Bristol-Myers Squibb, Clovis Oncology, QED Therapeutics, Seattle Genetics, Foundation Medicine, Heron Therapeutics, Driver Inc. within a year from the submission, but unrelated to this Editorial. The other authors have no conflicts of interest to declare.
Comment on
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Avelumab in metastatic urothelial carcinoma after platinum failure (JAVELIN Solid Tumor): pooled results from two expansion cohorts of an open-label, phase 1 trial.Lancet Oncol. 2018 Jan;19(1):51-64. doi: 10.1016/S1470-2045(17)30900-2. Epub 2017 Dec 5. Lancet Oncol. 2018. PMID: 29217288 Free PMC article. Clinical Trial.
References
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- De Santis M, Bellmunt J, Mead G, et al. Randomized phase II/III trial assessing gemcitabine/carboplatin and methotrexate/carboplatin/vinblastine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: EORTC study 30986. J Clin Oncol 2012;30:191-9. 10.1200/JCO.2011.37.3571 - DOI - PMC - PubMed
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- Rosenberg JE, Hoffman-Censits J, Powles T, et al. Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial. Lancet 2016;387:1909-20. 10.1016/S0140-6736(16)00561-4 - DOI - PMC - PubMed
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