Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Sep;27(5):1819-1827.
doi: 10.1007/s10741-021-10178-7. Epub 2022 Feb 4.

Evaluation of donor heart for transplantation

Affiliations
Review

Evaluation of donor heart for transplantation

Robert Tatum et al. Heart Fail Rev. 2022 Sep.

Abstract

Cardiac transplantation is considered the gold-standard treatment option for patients suffering from end-stage heart failure refractory to maximum medical therapy. A major determinant of graft function and recipient survival is a comprehensive evaluation of the donor allograft. Challenges arise when designing and implementing an evidence-based donor evaluation protocol due to the number of influential donor-specific characteristics and the complex interactions that occur between them. Here, we present our systematic approach to donor evaluation by examining the impact that relevant donor variables have on graft function and recipient outcomes.

Keywords: Donor evaluation; Heart transplantation; Ischemic time; Size-matching.

PubMed Disclaimer

References

    1. Alraies MC, Eckman P. Adult heart transplant: indications and outcomes. J Thorac Dis. 2014 doi: 10.3978/j.issn.2072-1439.2014.06.44. - DOI - PMC - PubMed
    1. Mancini D, Lietz K. Selection of cardiac transplantation candidates in 2010. Circulation. 2010 doi: 10.1161/CIRCULATIONAHA.109.858076. - DOI - PubMed
    1. Colvin-Adams M, Valapour M, Hertz M, Heubner B, Paulson K, Dhungel V, Skeans MA, Edwards L, Ghimire V, Waller C, Cherikh WS, Kasiske BL, Snyder JJ, Israni AK. Lung and heart allocation in the United States. Am J Transplant. 2012;12(12):3213-3234. 10.1111/j.1600-6143.2012.04258.x - PubMed
    1. Persad G, Wertheimer A, Emanuel EJ. Principles for allocation of scarce medical interventions. Lancet. 2009. 10.1016/S0140-6736(09)60137-9 - PubMed
    1. Estep J, Soltesz E, Cogswell R. The new heart transplant allocation system: Early observations and mechanical circulatory support considerations. J Thorac Cardiovasc Surg. 2020;S0022-5223(20)32638-6. 10.1016/j.jtcvs.2020.08.113 - PubMed