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. 1986 Jan 29;134(2):565-71.
doi: 10.1016/s0006-291x(86)80457-0.

Muscle proteins related to microtubule associated protein-2 are substrates for an insulin-stimulatable kinase

T W Sturgill, L B Ray

Muscle proteins related to microtubule associated protein-2 are substrates for an insulin-stimulatable kinase

T W Sturgill et al. Biochem Biophys Res Commun. .

Abstract

High molecular weight muscle protein(s), present as a "doublet" (approximately 320 and approximately 290 kDa apparent molecular weight) in partially purified preparations of inhibitor-2 from rabbit skeletal muscle, and homogeneous bovine brain microtubule associated protein-2 are both in vitro substrates for a soluble insulin-stimulatable serine/threonine kinase in 3T3-L1 adipocytes. The high molecular weight muscle substrate "doublet" was specifically immunoprecipitated by affinity-purified anti-microtubule associated protein-2 antibody.

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