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Comment
. 2022 Feb 14;40(2):134-135.
doi: 10.1016/j.ccell.2022.01.011. Epub 2022 Feb 3.

Metastasis and organotropism: A look through the lens of large-scale clinical sequencing data

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Free article
Comment

Metastasis and organotropism: A look through the lens of large-scale clinical sequencing data

Alexander Coulton et al. Cancer Cell. .
Free article

Abstract

In Cell, Nguyen et al. utilize targeted panel sequencing combined with electronic health record data to study metastasis and organotropism in a large cohort of 25,775 patients. Their genomic and clinical data have been made freely available as a resource for use by the community.

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  • Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients.
    Nguyen B, Fong C, Luthra A, Smith SA, DiNatale RG, Nandakumar S, Walch H, Chatila WK, Madupuri R, Kundra R, Bielski CM, Mastrogiacomo B, Donoghue MTA, Boire A, Chandarlapaty S, Ganesh K, Harding JJ, Iacobuzio-Donahue CA, Razavi P, Reznik E, Rudin CM, Zamarin D, Abida W, Abou-Alfa GK, Aghajanian C, Cercek A, Chi P, Feldman D, Ho AL, Iyer G, Janjigian YY, Morris M, Motzer RJ, O'Reilly EM, Postow MA, Raj NP, Riely GJ, Robson ME, Rosenberg JE, Safonov A, Shoushtari AN, Tap W, Teo MY, Varghese AM, Voss M, Yaeger R, Zauderer MG, Abu-Rustum N, Garcia-Aguilar J, Bochner B, Hakimi A, Jarnagin WR, Jones DR, Molena D, Morris L, Rios-Doria E, Russo P, Singer S, Strong VE, Chakravarty D, Ellenson LH, Gopalan A, Reis-Filho JS, Weigelt B, Ladanyi M, Gonen M, Shah SP, Massague J, Gao J, Zehir A, Berger MF, Solit DB, Bakhoum SF, Sanchez-Vega F, Schultz N. Nguyen B, et al. Cell. 2022 Feb 3;185(3):563-575.e11. doi: 10.1016/j.cell.2022.01.003. Cell. 2022. PMID: 35120664 Free PMC article.

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