Why the application of IVIG might be beneficial in patients with COVID-19 - Authors' reply

Aurélien Mazeraud¹, Michel Wolff², Bruno Lucas³, Tarek Sharshar²

Affiliations

¹ Service d'Anesthésie-Réanimation, Groupe Hospitalier Université Paris Psychiatrie et Neurosciences, Pôle Neuro, 75014 Paris, France; Department of Neurosiences, Université de Paris, Paris, France. Electronic address: a.mazeraud@ghu-paris.fr.
² Service d'Anesthésie-Réanimation, Groupe Hospitalier Université Paris Psychiatrie et Neurosciences, Pôle Neuro, 75014 Paris, France; Department of Neurosiences, Université de Paris, Paris, France.
³ Institut Cochin, Centre National de la Recherche Scientifique UMR8104, INSERM U1016, Paris, France.

PMID: 35120612
PMCID: PMC8806197
DOI: 10.1016/S2213-2600(21)00550-6

Comment

Why the application of IVIG might be beneficial in patients with COVID-19 - Authors' reply

Aurélien Mazeraud et al. Lancet Respir Med. 2022 Feb.

. 2022 Feb;10(2):e16.

doi: 10.1016/S2213-2600(21)00550-6.

Authors

Aurélien Mazeraud¹, Michel Wolff², Bruno Lucas³, Tarek Sharshar²

Affiliations

¹ Service d'Anesthésie-Réanimation, Groupe Hospitalier Université Paris Psychiatrie et Neurosciences, Pôle Neuro, 75014 Paris, France; Department of Neurosiences, Université de Paris, Paris, France. Electronic address: a.mazeraud@ghu-paris.fr.
² Service d'Anesthésie-Réanimation, Groupe Hospitalier Université Paris Psychiatrie et Neurosciences, Pôle Neuro, 75014 Paris, France; Department of Neurosiences, Université de Paris, Paris, France.
³ Institut Cochin, Centre National de la Recherche Scientifique UMR8104, INSERM U1016, Paris, France.

PMID: 35120612
PMCID: PMC8806197
DOI: 10.1016/S2213-2600(21)00550-6

No abstract available

PubMed Disclaimer

Conflict of interest statement

We declare no competing interests.

Comment on

Intravenous immunoglobulins in patients with COVID-19-associated moderate-to-severe acute respiratory distress syndrome (ICAR): multicentre, double-blind, placebo-controlled, phase 3 trial.
Mazeraud A, Jamme M, Mancusi RL, Latroche C, Megarbane B, Siami S, Zarka J, Moneger G, Santoli F, Argaud L, Chillet P, Muller G, Bruel C, Asfar P, Beloncle F, Reignier J, Vinsonneau C, Schimpf C, Amour J, Goulenok C, Lemaitre C, Rohaut B, Mateu P, De Rudnicki S, Mourvillier B, Declercq PL, Schwebel C, Stoclin A, Garnier M, Madeux B, Gaudry S, Bailly K, Lamer C, Aegerter P, Rieu C, Sylla K, Lucas B, Sharshar T. Mazeraud A, et al. Lancet Respir Med. 2022 Feb;10(2):158-166. doi: 10.1016/S2213-2600(21)00440-9. Epub 2021 Nov 11. Lancet Respir Med. 2022. PMID: 34774185 Free PMC article. Clinical Trial.
Why the application of IVIG might be beneficial in patients with COVID-19.
Kindgen-Milles D, Feldt T, Jensen BEO, Dimski T, Brandenburger T. Kindgen-Milles D, et al. Lancet Respir Med. 2022 Feb;10(2):e15. doi: 10.1016/S2213-2600(21)00549-X. Lancet Respir Med. 2022. PMID: 35120611 Free PMC article. No abstract available.

References

1. Alejandria MM, Lansang MAD, Dans LF, Mantaring JB. Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock. Cochrane Database Syst Rev. 2013;9 - PMC - PubMed
1. Welte T, Dellinger RP, Ebelt H, et al. Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study) Intensive Care Med. 2018;44:438–448. - PMC - PubMed
1. Taccone FS, Stordeur P, De Backer D, Creteur J, Vincent J-L. Gamma-globulin levels in patients with community-acquired septic shock. Shock. 2009;32:379–385. - PubMed
1. Hadjadj J, Yatim N, Barnabei L, et al. Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients. Science. 2020;369:718–724. - PMC - PubMed
1. Leisman DE, Ronner L, Pinotti R, et al. Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes. Lancet Respir Med. 2020;8:1233–1244. - PMC - PubMed

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions

Substances

Actions

LinkOut - more resources

Full Text Sources
- Elsevier Science

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Why the application of IVIG might be beneficial in patients with COVID-19 - Authors' reply

Affiliations

Why the application of IVIG might be beneficial in patients with COVID-19 - Authors' reply

Authors

Affiliations

Conflict of interest statement

Comment on

References

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources