Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug;26(8):2600-2612.
doi: 10.1007/s10461-022-03602-y. Epub 2022 Feb 4.

Implementation of South Africa's Central Chronic Medicine Dispensing and Distribution Program for HIV Treatment: A Qualitative Evaluation

Affiliations

Implementation of South Africa's Central Chronic Medicine Dispensing and Distribution Program for HIV Treatment: A Qualitative Evaluation

Laura M Bogart et al. AIDS Behav. 2022 Aug.

Abstract

We used the Practical, Robust Implementation and Sustainability Model to evaluate implementation of South Africa's Central Chronic Medicine Dispensing and Distribution (CCMDD) program, a differentiated service delivery program which allows clinically stable HIV-positive patients to receive antiretroviral therapy refills at clinic- or community-based pick-up points. Across ten clinics, we conducted 109 semi-structured interviews with stakeholders (pick-up point staff, CCMDD service providers and administrators) and 16 focus groups with 138 patients. Participants had highly favorable attitudes and said CCMDD decreased stigma concerns. Patient-level barriers included inadequate education about CCMDD and inability to get refills on designated dates. Organizational-level barriers included challenges with communication and transportation, errors in medication packaging and tracking, rigid CCMDD rules, and inadequate infrastructure. Recommendations included: (1) provide patient education and improve communication around refills (at the patient level); (2) provide dedicated space and staff, and ongoing training (at the organizational/clinic level); and (3) allow for prescription renewal at pick-up points and less frequent refills, and provide feedback to clinics (at the CCMDD program level).

Keywords: Antiretroviral therapy; Differentiated service delivery; HIV/AIDS; Implementation science; Qualitative; South Africa.

PubMed Disclaimer

Conflict of interest statement

The authors have no relevant financial or non-financial interests to disclose; the authors have no conflicts of interest to declare that are relevant to the content of this article; all authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript; and the authors have no financial or proprietary interests in any material discussed in this article.

References

    1. AIDSinfo|UNAIDS. 2021. Available from: http://aidsinfo.unaids.org/.
    1. Avert. HIV and AIDS in South Africa 2020. Updated April 15, 2020. Available from: https://www.avert.org/professionals/hiv-around-world/sub-saharan-africa/....
    1. UNAIDS Joint United Nations Programme on HIV/AIDS. Understanding fast-track-accelerating action to end the AIDS epidemic by 2030 Geneva, Switzerland. Updated June 2015; cited 2021. Available from: https://www.unaids.org/sites/default/files/media_asset/201506_JC2743_Und....
    1. Nachega JB, Adetokunboh O, Uthman OA, Knowlton AW, Altice FL, Schechter M, et al. Community-based interventions to improve and sustain antiretroviral therapy adherence, retention in HIV care and clinical outcomes in low-and middle-income countries for achieving the UNAIDS 90-90-90 targets. Curr HIV/AIDS Rep. 2016;13(5):241–255. doi: 10.1007/s11904-016-0325-9. - DOI - PMC - PubMed
    1. Okoboi S, Ding E, Persuad S, Wangisi J, Birungi J, Shurgold S, et al. Community-based ART distribution system can effectively facilitate long-term program retention and low-rates of death and virologic failure in rural Uganda. AIDS Res Ther. 2015;12(1):1–9. doi: 10.1186/s12981-015-0077-4. - DOI - PMC - PubMed