Is the attenuated humoral response to COVID-19 vaccination in anti-TNF users relevant?
- PMID: 35123675
- PMCID: PMC8813199
- DOI: 10.1016/S2468-1253(22)00040-1
Is the attenuated humoral response to COVID-19 vaccination in anti-TNF users relevant?
Conflict of interest statement
TC declares no competing interests. LET has received grants and consulting fees from AbbVie Canada, Pfizer Canada, Takeda Canada, Janssen Canada, Roche Canada, Merck Canada, Sandoz Canada, and Janssen Canada; consulting fees from Celltron Canada; and payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or education events from Takeda Canada, Janssen Canada, and AbbVie Canada.
Comment on
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COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study.Lancet Gastroenterol Hepatol. 2022 Apr;7(4):342-352. doi: 10.1016/S2468-1253(22)00005-X. Epub 2022 Feb 4. Lancet Gastroenterol Hepatol. 2022. PMID: 35123676 Free PMC article.
References
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- Kennedy NA, Goodhand JR, Bewshea C, et al. Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab. Gut. 2021;70:865–875. - PubMed
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- Alexander JL, Kennedy NA, Ibraheim H, et al. COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study. Lancet Gastroenterol Hepatol. 2020 doi: 10.1016/S2468-1253(22)00005-X. published online Feb 3. - DOI - PMC - PubMed
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- Khoury DS, Cromer D, Reynaldi A, et al. Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nat Med. 2021;27:1205–1211. - PubMed
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- Khan N, Patel D, Xie D, Pernes T, Lewis J, Yang Y-X. Are patients with inflammatory bowel disease at an increased risk of developing SARS-CoV-2 than patients without inflammatory bowel disease? Results from a nationwide veterans' affairs cohort study. Am J Gastroenterol. 2021;116:808–810. - PubMed
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