Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Apr;84(4):e13-e15.
doi: 10.1016/j.jinf.2022.01.044. Epub 2022 Feb 3.

Antibody titers and breakthrough infections with Omicron SARS-CoV-2

Chloé Dimeglio  1 , Marion Migueres  2 , Jean-Michel Mansuy  3 , Sylvie Saivin  4 , Marcel Miedougé  3 , Sabine Chapuy-Regaud  2 , Jacques Izopet  2
Affiliations

Antibody titers and breakthrough infections with Omicron SARS-CoV-2

Chloé Dimeglio et al. J Infect. 2022 Apr.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest The authors declare no conflict of interest

Figures

Fig. 1
Fig. 1
: Distributions of binding antibody concentrations before infection with Delta or Omicron Sars-CoV-2 variants.
See this image and copyright information in PMC

Comment in

  • High rate of reinfection with the SARS-CoV-2 Omicron variant.
    Nguyen NN, Houhamdi L, Hoang VT, Stoupan D, Fournier PE, Raoult D, Colson P, Gautret P. Nguyen NN, et al. J Infect. 2022 Aug;85(2):174-211. doi: 10.1016/j.jinf.2022.04.034. Epub 2022 Apr 23. J Infect. 2022. PMID: 35472367 Free PMC article. No abstract available.

References

    1. Kuhlmann C., Konstanze Mayer C., Claassen M., Maponga T., Burgers W.A., Keeton R. Breakthrough infections with SARS-CoV-2 omicron despite mRNA vaccine booster dose. The Lancet. 2022 Jan 18 doi: 10.1016/S0140-6736(22)00090-3. - DOI - PMC - PubMed
    1. Lu L., Mok B.W., Chen L.L., Chan J.M., Tsang O.T., Lam B.H., et al. Neutralization of SARS-CoV-2 Omicron variant by sera from BNT162b2 or Coronavac vaccine recipients. Clin Infect Dis. 2021 Dec 16:ciab1041. doi: 10.1093/cid/ciab1041. - DOI - PMC - PubMed
    1. Dimeglio C., Herin F., Martin-Blondel G., Miedougé M., Izopet J. Antibody titers and protection against a SARS-CoV-2 infection. J Infect. 2021 Sep 21;(21):S0163–S4453. doi: 10.1016/j.jinf.2021.09.013. 00483-7. - DOI - PMC - PubMed
    1. Faustini S., Shields A., Banham G., Wall N., Al-Taei S., Tanner C., et al. Cross reactivity of spike glycoprotein induced antibody against delta and omicron variants before and after third SARS-CoV-2 vaccine dose in healthy and immunocompromised individuals. J Infect. 2022 Jan 10;(22):S0163–S4453. doi: 10.1016/j.jinf.2022.01.002. 00002-0. - DOI - PMC - PubMed
    1. Chapuy-Regaud S., Miédougé M., Abravanel F., Da Silva I., Porcheron M., Fillaux J., et al. Evaluation of three quantitative anti-SARS-CoV-2 antibody immunoassays. Microbiol Spectr. 2021 Dec 22;9(3) doi: 10.1128/spectrum.01376-21. - DOI - PMC - PubMed