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Case Reports
. 2021 Oct-Dec;36(4):429-431.
doi: 10.4103/ijnm.ijnm_61_21. Epub 2021 Dec 15.

Rare Presentation of Radiation-induced Sarcoma Detected on F-18 FDG Positron Emission Tomography/Computed Tomography in a Treated Case of Giant Cell Tumor

Indraja D Dev  1 , Ameya D Puranik  1 , Venkatesh Rangarajan  1 , Nilendu C Purandare  1 , Archi Agrawal  1 , Sneha Shah  1 , Sayak Choudhury  1
Affiliations
Case Reports

Rare Presentation of Radiation-induced Sarcoma Detected on F-18 FDG Positron Emission Tomography/Computed Tomography in a Treated Case of Giant Cell Tumor

Indraja D Dev et al. Indian J Nucl Med. 2021 Oct-Dec.

Abstract

Giant cell tumors (GCTs) are benign bone lesions which are treated with curettage and bone grafting. Infrequently, GCTs show local site recurrences which are then treated with either surgical excision or radiation therapy. Radiation-induced sarcoma is rarely seen as a late complication of radiation therapy which needs to be differentiated from recurrent GCT. We report one such rare case of radiation-induced sarcoma detected on Flourine-18 fluorodeoxyglucose (18F FDG) positron emission tomography/computed tomography in a 40-year-old male who was treated with radiation therapy for recurrent GCT 9 years ago.

Keywords: FDG positron emission tomography/computed tomography; giant cell tumor; radiation-induced sarcoma.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Maximum intensity projection (a- red arrow) shows intense uptake in right sacroiliac joint region. Fused positron emission tomography/computed tomography images (b and c) show intense heterogeneous FDG uptake in right sacroiliac joint which corresponds to destructive soft-tissue mass extending into neural foramina with cortical destruction and expansion seen on transaxial and coronal computed tomography images (d-g)
See this image and copyright information in PMC

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