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. 2021 Nov 29:26:111.
doi: 10.4103/jrms.JRMS_501_20. eCollection 2021.

How is insulin-like growth factor-1 correlated with retinopathy of prematurity?

Nahid Jafari  1 , Arezoo Karimi Moghadam  2 , Naeeme Taslimi Taleghani  3 , Neda Hosseini Nezhad  4 , Nima Motamed  5 , Ahmad Jalilvand  6
Affiliations

How is insulin-like growth factor-1 correlated with retinopathy of prematurity?

Nahid Jafari et al. J Res Med Sci. .

Abstract

Background: Evaluation of insulin-like growth factor-1 (IGF-1) association with retinopathy of prematurity (ROP) is our object.

Materials and methods: This study was conducted on IGF-1 levels of 40 neonates <34 weeks gestational age and 2000 g at 1st week and 4-6 weeks after birth. All participants were evaluated for ROP after 31 weeks of gestation.

Results: IGF-1 levels showed a significant difference between neonates ≤1500 and 1500-2000 g (1 and 4-6 weeks, P = 0.008, P = 0.039, respectively). No significant association was found between IGF-1 and ROP.

Conclusion: Finding a meaningful association between IGF-1 and ROP requires consideration of factors affecting the IGF-1.

Keywords: Insulin-like growth factor-1; preterm birth; retinopathy of prematurity.

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Conflict of interest statement

There are no conflicts of interest.

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