Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Nov-Dec;14(6):847-852.
doi: 10.25122/jml-2021-0354.

Delayed breast reconstruction with tram-flap and various modifications after radical mastectomy

Affiliations

Delayed breast reconstruction with tram-flap and various modifications after radical mastectomy

Ivan Ivanovich Smolanka et al. J Med Life. 2021 Nov-Dec.

Abstract

This study describes the experience of radical mastectomies with simultaneous breast reconstruction using TRAM flap in patients with inflammatory breast cancer. The study aimed to evaluate the effectiveness of primary breast reconstruction using the TRAM-flap procedure in patients with an inflammatory form of breast cancer. Our work is associated with some deviation from generally accepted standards: delayed breast reconstruction after radical mastectomy for inflammatory breast cancer. We describe the experience of radical mastectomies with the simultaneous reconstruction of the breast using a TRAM flap in patients with inflammatory breast cancer. This study included 12 patients diagnosed with breast cancer stages IIIB and IIIC. Almost all patients (eleven out of twelve patients) underwent radical mastectomy with one-stage reconstruction using a TRAM flap after chemotherapy. Two years later, one patient (8.3%) showed disease progression in the form of distant metastases in the bones of the spine. One patient (8.3%) had a regional relapse in the displaced flap near the postoperative scar. The rest of the patients (83.4%) showed no signs of continuing the disease. Patients with one-stage breast reconstruction improved socially, and their subjective well-being was better than those who underwent radical mastectomy without reconstruction. Experience in performing one-stage reconstructions in the surgical treatment of patients with inflammatory breast cancer is a reason for restrained optimism regarding the possibility and feasibility of these operations.

Keywords: inflammatory breast cancer; intra-arterial chemotherapy; oncoplastic surgery; simultaneous breast plastic surgery.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
The vascular anastomosis was made between the inferior epigastric artery and a vein with the internal thoracic artery and vein on the left.

References

    1. Scaranelo AM, Lord B, Eiada R, Hofer SO. Imaging approaches and findings in the reconstructed breast: a pictorial essay. Can Assoc Radiol J. 2011 Feb;62(1):60–72. doi: 10.1016/j.carj.2010.09.010. - DOI - PubMed
    1. Cheng E, Ko D, Nguyen M, Moo TA, Andreopoulou E, Hoda SA, D’Alfonso TM. Residual Pure Intralymphatic Breast Carcinoma Following Neoadjuvant Chemotherapy Is Indicative of Poor Clinical Outcome, Even in Node-Negative Patients. Am J Surg Pathol. 2017 Sep;41(9):1275–1282. doi: 10.1097/PAS.0000000000000896. - DOI - PubMed
    1. Berishvili AI. 2011. Edematous-infiltrative form of breast cancer (clinical picture, diagnosis, treatment, prognosis factors - the topic of the thesis and abstract on the Higher Attestation Commission of the Russian Federation on January 14, 2012, Doctor of Medical Sciences.
    1. Ueno NT, Espinosa Ferandez JR, Cristofanilli M, Overmoyer B, Rea D, Berdichevski F, El-Shinawi M, Bellon J, Le-Petross HT, Lucci A, Babiera G, DeSnyder SM, Teshome M, Chang E, Lim B, Krishnamurthy S, Stauder MC, Parmar S, Mohamed MM, Alexander A, Woodward WA. International Consensus on the Clinical Management of Inflammatory Breast Cancer from the Morgan Welch Inflammatory Breast Cancer Research Program 10th Anniversary Conference. Journal of Cancer. 2018;9(8):1437–1447. doi: 10.7150/jca.23969. - DOI - PMC - PubMed
    1. Riggio AI, Varley KE, Welm AL. The lingering mysteries of metastatic recurrence in breast cancer. Br J Cancer 124, 13–26 (2021) - DOI - PMC - PubMed

LinkOut - more resources