Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 May;15(5):103743.
doi: 10.1016/j.arabjc.2022.103743. Epub 2022 Jan 29.

Sustainable adsorptive removal of antibiotic residues by chitosan composites: An insight into current developments and future recommendations

Eman M Abd El-Monaem  1 , Abdelazeem S Eltaweil  1 , Hala M Elshishini  2 , Mohamed Hosny  3 , Mohamed M Abou Alsoaud  4 , Nour F Attia  5 , Gehan M El-Subruiti  1 , Ahmed M Omer  4
Affiliations
Review

Sustainable adsorptive removal of antibiotic residues by chitosan composites: An insight into current developments and future recommendations

Eman M Abd El-Monaem et al. Arab J Chem. 2022 May.

Abstract

During COVID-19 crisis, water pollution caused by pharmaceutical residuals have enormously aggravated since millions of patients worldwide are consuming tons of drugs daily. Antibiotics are the preponderance pharmaceutical pollutants in water bodies that surely cause a real threat to human life and ecosystems. The excellent characteristics of chitosan such as nontoxicity, easy functionality, biodegradability, availability in nature and the abundant hydroxyl and amine groups onto its backbone make it a promising adsorbent. Herein, we aimed to provide a comprehensive overview of recent published research papers regarding the removal of antibiotics by chitosan composite-based adsorbents. The structure, ionic form, optimum removal pH and λmax of the most common antibiotics including Tetracycline, Ciprofloxacin, Amoxicillin, Levofloxacin, Ceftriaxone, Erythromycin, Norfloxacin, Ofloxacin, Doxycycline, Cefotaxime and Sulfamethoxazole were summarized. The development of chitosan composite-based adsorbents in order to enhance their adsorption capacity, reusability and validity were presented. Moreover, the adsorption mechanisms of these antibiotics were explored to provide more information about adsorbate-adsorbent interactions. Besides the dominant factors on the adsorption process including pH, dosage, coexisting ions, etc. were discussed. Moreover, conclusions and future recommendations are provided to inspire for further researches.

Keywords: Adsorption; Chitosan; Ionic form; Mechanism; Pharmaceutical residue.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

None
Graphical abstract
Fig. 1
Fig. 1
Most common types of antibiotic wastes.
Fig. 2
Fig. 2
Production of chitosan from crustacean (Duan et al., 2019). Copyright Elsevier 2019.
Fig. 3
Fig. 3
(a) Scheme of synthesis of CTM@Fe3O4, (b) SEM image, (c) TEM image, (d) HRTEM image and (e) d-spacing and SAED of CTM@Fe3O4. Copyright Elsevier.
Fig. 4
Fig. 4
Multiform of (a) TC and (b) pH-dependent speciation of TC (Zhao et al., 2011). Copyright 2021, Springer.
Fig. 5
Fig. 5
Schematic diagram of Na-Mt-CMCs) composite. Color legend for the atoms in the picture: Mg (purple), Al (green), Si (blue), C (gray), O (red), N (yellow), and H (white) (Ma et al., 2019). Copyright, Elsevier, 2021.
Fig. 6
Fig. 6
The proposed adsorption mechanisms of TC onto BCs-Fe/S composite (Liu et al., 2019). Copyright, Elsevier, 2021.
Fig. 7
Fig. 7
Schematic illustration of CIF adsorption mechanism onto Fe-CS NCs at different pH (Rasoulzadeh et al., 2019). Copyright, Elsevier, 2021.
Fig. 8
Fig. 8
BET of (a) Cs, SiO2/Fe3O4 and Cs-grafted SiO2/Fe3O4 and (b) effect of pH on the adsorption of CIP onto Cs-grafted SiO2/Fe3O4 (Danalıoğlu et al., 2018). Copyright, Elsevier, 2021.
Fig. 9
Fig. 9
(a) Effect of solution pH on OFL adsorption (b) Distribution of OFL species as a function of pH (Zhu et al., 2018). Copyright, Taylor & Francis, 2021.
Fig. 10
Fig. 10
(a) Schematic illustration of preparation of NiFe2O4/COF/CS/TPA nanocomposites film (NCCT) and adsorption of CTX on NCCT (Kentsa et al., 2020). Copyright, Elsevier, 2021. (b) Schematic representation for the fabrication of AmCsC and the adsorption mechanism of SMX on AmCsC.
See this image and copyright information in PMC

References

    1. Abd El-Hack M.E., El-Saadony M.T., Shafi M.E., Zabermawi N.M., Arif M., Batiha G.E., Khafaga A.F., Abd El-Hakim Y.M., Al-Sagheer A.A. Antimicrobial and antioxidant properties of chitosan and its derivatives and their applications: a review. Int. J. Biol. Macromol. 2020;164:2726–2744. - PubMed
    1. Abdelfatah A.M., Fawzy M., El-Khouly M.E., Eltaweil A.S. Efficient adsorptive removal of tetracycline from aqueous solution using phytosynthesized nano-zero valent iron. J. Saudi Chem. Soc. 2021;25:101365.
    1. Acuna G., Johnston J., Young L., Martin W. In-vitro studies with ceftazidime against aerobic Gram-negative bacilli and Bacteroides fragilis group. J. Antimicrob. Chemother. 1981;8:83–89. - PubMed
    1. Afzal M.Z., Sun X.-F., Liu J., Song C., Wang S.-G., Javed A. Enhancement of ciprofloxacin sorption on chitosan/biochar hydrogel beads. Sci. Total Environ. 2018;639:560–569. - PubMed
    1. Afzal M.Z., Yue R., Sun X.-F., Song C., Wang S.-G. Enhanced removal of ciprofloxacin using humic acid modified hydrogel beads. J. Colloid Interface Sci. 2019;543:76–83. - PubMed

LinkOut - more resources