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. 1986 Mar;29(3):386-94.
doi: 10.1021/jm00153a014.

Imidazo[2,1-b]benzothiazoles. 2. New immunosuppressive agents

T Mase, H Arima, K Tomioka, T Yamada, K Murase

Imidazo[2,1-b]benzothiazoles. 2. New immunosuppressive agents

T Mase et al. J Med Chem. 1986 Mar.

Abstract

A series of 2-phenylimidazo[2,1-b]benzothiazole derivatives was prepared and tested for immunological activities. Some of the compounds showed significant suppressive activity of delayed type hypersensitivity (DTH) without inhibition of humoral immunity in mice by oral administration. The most active compound was 2-(m-hydroxyphenyl)imidazo[2,1-b]benzothiazole (20).

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