Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022;4(1):49.
doi: 10.1007/s42399-022-01132-1. Epub 2022 Jan 31.

High-Flow Nasal Oxygenation and Its Applicability in COVID Patients

Affiliations
Review

High-Flow Nasal Oxygenation and Its Applicability in COVID Patients

Raafay Mehmood et al. SN Compr Clin Med. 2022.

Abstract

High-flow nasal oxygenation (HFNO) is a type of oxygen therapy that provides humidified and heated oxygen through a nasal cannula at much higher flow rates than standard oxygen therapy, while also allowing control over the fraction of inspired oxygen (FIO2). Compared to standard oxygen therapy, it is much more comfortable for the patient and seems to alleviate most of the problems associated with standard oxygen therapy, such as dry nose, dry throat and nasal pain. It also provides a variety of benefits that can reduce the incidence of escalating treatment and initiating mechanical ventilation in COVID patients with acute hypoxemic respiratory failure (AHRF). This article provides an overview of HFNO and its current applications in COVID patients during the pandemic.

Keywords: Anaesthesia; COVID; High-flow nasal oxygenation; Intensive care; Oxygen therapy; Pre-oxygenation; Respiratory failure.

PubMed Disclaimer

Conflict of interest statement

Conflict of InterestThe authors declare no competing interests.

References

    1. Rouadi P, Baroody FM, Abbott D, et al (1999) A technique to measure the ability of the human nose to warm and humidify air. J Appl Physiol. 10.1152/jappl.1999.87.1.400 - PubMed
    1. Chanques G, Constantin JM, Sauter M, et al (2009) Discomfort associated with underhumidified high-flow oxygen therapy in critically ill patients. Intensive Care Med. 10.1007/s00134-009-1456-x - PubMed
    1. Salah B, Dinh Xuan AT, Fouilladieu JL, et al (1988) Nasal mucociliary transport in healthy subjects is slower when breathing dry air. Eur Respir J - PubMed
    1. L’Her E, Deye N, Lellouche F, et al (2005) Physiologic effects of noninvasive ventilation during acute lung injury. Am J Respir Crit Care Med. 10.1164/rccm.200402-226OC - PubMed
    1. Girou E, Brun-Buisson C, Taillé S, et al (2003) Secular Trends in Nosocomial Infections and Mortality Associated with Noninvasive Ventilation in Patients with Exacerbation of COPD and Pulmonary Edema. J Am Med Assoc. 10.1001/jama.290.22.2985 - PubMed

LinkOut - more resources