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Comment
. 2022 Nov 1;276(5):e632-e633.
doi: 10.1097/SLA.0000000000005268. Epub 2021 Oct 20.

Response to Comment on: Hasselgren K, et al ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO. Ann Surg. 2021;273(3):442-448

Kristina Hasselgren  1 , Bard I Røsok  2 , Peter N Larsen  3 , Ernesto Sparrelid  4 , Gert Lindell  5 , Nicolai A Schultz  6 , Bjorn A Bjørnbeth  7 , Bengt Isaksson  8 , Anna Lindhoff Larsson  1 , Magnus Rizell  9 , Bergthor Björnsson  10 , Per Sandström  10
Affiliations
Comment

Response to Comment on: Hasselgren K, et al ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO. Ann Surg. 2021;273(3):442-448

Kristina Hasselgren et al. Ann Surg. .
No abstract available

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Conflict of interest statement

The author reports no conflicts of interest.

Comment on

References

    1. Hasselgren K, Røsok BI, Larsen PN, et al. ALPPS improves survival compared with TSH in patients affected of CRLM: survival analysis from the randomized controlled trial LIGRO. Ann Surg. 2021;273:442–448.
    1. O’Neill RT. Secondary endpoints cannot be validly analyzed if the primary endpoint does not demonstrate clear statistical significance. Control Clin Trials. 1997;18:550–556. discussion 561–7.
    1. Mascha EJ, Vetter TR. Significance, errors, power, and sample size: the blocking and tackling of statistics. Anesth Analg. 2018;126: 691–698.
    1. Linecker M, Björnsson B, Stavrou FGA. et al. Risk adjustment in ALPPS is associated with a dramatic decrease in early mortality and morbidity. Ann Surg. 2017;266:779–786.
    1. Regimbeau JM, Cosse C, Kaiser G, et al. Feasibility, safety and efficacy of two-stage hepatectomy for bilobar liver metastases of colorectal cancer: a LiverMetSurvey analysis. HPB (Oxford). 2017;19:396–405.

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