Beware the drug titration paradox. Comment on Br J Anaesth 2021; 127: 704-12
- PMID: 35131097
- DOI: 10.1016/j.bja.2022.01.004
Beware the drug titration paradox. Comment on Br J Anaesth 2021; 127: 704-12
Keywords: BIS; anaesthesia; delirium; drug titration paradox; electroencephalography; neurocognitive dysfunction; pharmacodynamics; titration.
Conflict of interest statement
Declarations of interest The authors declare that they have no conflicts of interest.
Comment in
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The drug titration paradox: something obvious finally understood.Br J Anaesth. 2022 Jun;128(6):900-902. doi: 10.1016/j.bja.2022.03.007. Epub 2022 Apr 7. Br J Anaesth. 2022. PMID: 35397881
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Anaesthetic depth and delirium after major surgery: a randomised clinical trial.Br J Anaesth. 2021 Nov;127(5):704-712. doi: 10.1016/j.bja.2021.07.021. Epub 2021 Aug 28. Br J Anaesth. 2021. PMID: 34465469 Free PMC article. Clinical Trial.