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Case Reports
. 2022 Feb 7;15(2):e247333.
doi: 10.1136/bcr-2021-247333.

Digital ischaemia and necrosis from oxaliplatin

Charity Huang  1   2 , Leslie Storey  3 , Uzair Chaudhary  4   2
Affiliations
Case Reports

Digital ischaemia and necrosis from oxaliplatin

Charity Huang et al. BMJ Case Rep. .

Abstract

Oxaliplatin is a chemotherapeutic agent used in a variety of malignancies such as colorectal cancer and pancreatic cancer. It is a platinum derivative that results in direct cell cytotoxicity with resultant cell death. The most common side effects often noted are neurotoxicity, nausea, vomiting, diarrhoea, hepatotoxicity and myelosuppression. Oxaliplatin induced digital ischaemia and necrosis is a rare side effect that was observed in our patient. In general, digital ischaemia is a rare vascular disorder that is often associated with autoimmune disease. A patient with digital ischaemia due to oxaliplatin will be described in this case report.

Keywords: cancer intervention; chemotherapy; contraindications and precautions; musculoskeletal and joint disorders; urological cancer.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Digital ischaemia can be seen on the tips of the middle fingers on bilateral hands.
See this image and copyright information in PMC

References

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