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. 2022 Mar 29;98(13):538-539.
doi: 10.1212/WNL.0000000000200221. Epub 2022 Feb 7.

Translocator Protein 18 kDa PET Imaging Highlights Asymptomatic Isolated Cerebellar Dysplasia

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Translocator Protein 18 kDa PET Imaging Highlights Asymptomatic Isolated Cerebellar Dysplasia

Belen Pascual et al. Neurology. .
No abstract available

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Figure
Figure. MRI, 18F-FDG, and 11C-ER176 PET
MRI shows right hemispheric cerebellar dysplasia with abnormal folia orientation (red arrow) and decreased myelination (asterisk) but no increased fluid-attenuated inversion recovery (FLAIR) signal suggestive of inflammation. Dysplastic tissue displaced normal tissue (white arrow). PET is coregistered to MRI. FDG = fluorodeoxyglucose; SUV = standardized uptake value; VT = total distribution volume, calculated with the Logan plot and a metabolite-corrected arterial input function.

References

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    1. Laure-Kamionowska M, Maslinska D. Astroglia and microglia in cerebellar neuronal migration disturbances. Folia Neuropathol. 2007;45(4):205-212. - PubMed

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