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Case Reports
. 2022 Feb 8;15(2):e246641.
doi: 10.1136/bcr-2021-246641.

Synchronous oral squamous cell carcinoma and a lymphoproliferative disorder in an adult: a challenge in diagnosis and management

Troy Van der Groen  1 , Raymond Patrick Shupak  2   3 , Roderick Y Kim  4   3
Affiliations
Case Reports

Synchronous oral squamous cell carcinoma and a lymphoproliferative disorder in an adult: a challenge in diagnosis and management

Troy Van der Groen et al. BMJ Case Rep. .

Abstract

Synchronous primary malignancies present challenges in diagnosis, treatment sequencing and management. We present a rare case of a synchronous oral cavity and lymphoproliferative malignancy in a middle-age man. Our patient presented with a primary oral cavity squamous cell carcinoma and was subsequently found to have a secondary lymphoproliferative malignancy (chronic lymphocytic leukaemia/small lymphocytic lymphoma). The challenge of staging and sequencing of treatment is discussed. In addition, this case highlights the importance of multidisciplinary consultation, designing a personalised treatment plan that is coincident with the standard of care for each malignancy, and close follow-up.

Keywords: ear; head and neck cancer; head and neck surgery; nose and throat/otolaryngology; oral and maxillofacial surgery; otolaryngology / ENT.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Preoperative view of the primary right buccal squamous cell carcinoma.
Figure 2
Figure 2
A, representative coronal section of the initial CT neck with contrast with yellow arrow demonstrating right jugular chain lymphadenopathy. B, coronal section of the PET/CT showing generalised low SUV uptake. The white arrow corresponds to the same right enlarged cervical lymph seen in A.
Figure 3
Figure 3
A, postoperative view of the resected right buccal squamous cell carcinoma. This was allowed to heal by secondary intention with the aid of an acellular dermal matrix. B, right buccal resected specimen.
Figure 4
Figure 4
Intraoperative view of the right level 1, 2, 3, 4,5 neck dissection 6 months after the resection.
See this image and copyright information in PMC

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