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. 2021 Nov;38(Suppl 4):e44-e45.
doi: 10.12788/fp.0144.

Stopping Empagliflozin Unmasks Heart Failure

Morolake Amole  1 , Julio Leey-Casella  1   2
Affiliations

Stopping Empagliflozin Unmasks Heart Failure

Morolake Amole et al. Fed Pract. 2021 Nov.

Abstract

SGLT2 inhibitors have been shown to have a role in the management of heart failure in patients with type 2 diabetes mellitus, but there is a risk of exacerbation when discontinued.

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Conflict of interest statement

Author disclosures The authors report no actual or potential conflicts of interest with regard to this article.

References

    1. Thomas MC. Type 2 diabetes and heart failure: challenges and solutions. Curr Cardiol Rev. 2016;12(3):249–255. doi: 10.2174/1573403X12666160606120254. - DOI - PMC - PubMed
    1. Patorno E, Pawar A, Franklin J, et al. Empagliflozin and the risk of heart failure hospitalization in routine clinical care: a first analysis from the EMPRISE study. Circulation. 2019;139(25):2822–2830. doi: 10.1161/CIRCULATIONAHA.118.039177. - DOI - PMC - PubMed
    1. Packer M. Heart failure: the most important, preventable, and treatable cardiovascular complication of type 2 diabetes. Diabetes Care. 2018;41(1):11–13. doi: 10.2337/dci17-0052. - DOI - PubMed
    1. Thrainsdottir I, Aspelund T, Thorheirsson G, et al. The association between glucose abnormalities and heart failure in the population-based Reykjavík study. Diabetes Care. 2005;28(3):612–616. doi: 10.2337/diacare.28.3.612. - DOI - PubMed
    1. Bell D, Goncalves E. Heart failure in the patient with diabetes: epidemiology, aetiology, prognosis, therapy and the effect of glucose-lowering medications. Diabetes Obes Metab. 2019;21(6):1277–1290. doi: 10.1111/dom.13652. - DOI - PubMed

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