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Comment
. 2022 Feb 8;55(2):198-200.
doi: 10.1016/j.immuni.2022.01.008.

To be or not to be a hepatic niche macrophage

Emelie Barreby  1 , Myriam Aouadi  2
Affiliations
Free article
Comment

To be or not to be a hepatic niche macrophage

Emelie Barreby et al. Immunity. .
Free article

Abstract

While single-cell analyses have improved our understanding of liver macrophage heterogeneity, their localization and cellular interactions remain unclear. In a recent issue of Cell, Guilliams et al. provide strategies to localize liver macrophage populations and their communication with neighboring cells during health and disease.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.
    Guilliams M, Bonnardel J, Haest B, Vanderborght B, Wagner C, Remmerie A, Bujko A, Martens L, Thoné T, Browaeys R, De Ponti FF, Vanneste B, Zwicker C, Svedberg FR, Vanhalewyn T, Gonçalves A, Lippens S, Devriendt B, Cox E, Ferrero G, Wittamer V, Willaert A, Kaptein SJF, Neyts J, Dallmeier K, Geldhof P, Casaert S, Deplancke B, Ten Dijke P, Hoorens A, Vanlander A, Berrevoet F, Van Nieuwenhove Y, Saeys Y, Saelens W, Van Vlierberghe H, Devisscher L, Scott CL. Guilliams M, et al. Cell. 2022 Jan 20;185(2):379-396.e38. doi: 10.1016/j.cell.2021.12.018. Epub 2022 Jan 11. Cell. 2022. PMID: 35021063 Free PMC article.

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