Even old foes can learn sweet new tricks
- PMID: 35143767
- DOI: 10.1016/j.chom.2022.01.011
Even old foes can learn sweet new tricks
Abstract
In this issue of Cell Host and Microbe, Haslwanter et al. (2022) present a comprehensive investigation into the molecular and functional basis of 17D vaccine responses and into differences between antibody neutralization of the 17D and related African lineage strains to contemporary Central/South American strains, including the emergent YFV ES-504 strain.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests J.E.C. has served as a consultant for Luna Biologics, GlaxoSmithKline, and Merck Sharp & Dohme Corp.; he is a member of the Scientific Advisory Board of Meissa Vaccines and founder of IDBiologics. The Crowe laboratory at Vanderbilt University Medical Center has received sponsored research agreements for unrelated work from Takeda Pharmaceutical, IDBiologics, and AstraZeneca. Vanderbilt University, where the authors work, has previously applied for a patent for human antibodies for YFV.
Comment on
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Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies.Cell Host Microbe. 2022 Feb 9;30(2):248-259.e6. doi: 10.1016/j.chom.2021.12.009. Epub 2022 Jan 7. Cell Host Microbe. 2022. PMID: 34998466 Free PMC article.
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