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. 2022 Feb 10;12(1):2251.
doi: 10.1038/s41598-022-06293-6.

Negative impact of the hypopnea index or duration increase after a non-frame work surgery in patients with very severe obstructive sleep apnea

Ethan I Huang  1   2   3 , Shu-Yi Huang  4   5   6 , Yu-Ching Lin  4   7   5   8 , Chieh-Mo Lin  5   9 , Chin-Kuo Lin  5   9 , Ying-Chih Huang  10 , Chia-Yu Hsu  10 , Jian-An Su  11
Affiliations

Negative impact of the hypopnea index or duration increase after a non-frame work surgery in patients with very severe obstructive sleep apnea

Ethan I Huang et al. Sci Rep. .

Abstract

A non-framework surgery could change the postoperative components of breathing disturbances and increase the frequency or duration of hypopnea in patients with very severe obstructive sleep apnea (OSA). Either an increase of hypopnea index, which increases apnea-hypopnea index (AHI), or an increase of its duration raises the concern of worsening the oxygen desaturation and so morbidity and mortality associated with OSA. It is unclear how the oxygen saturation would change in those having increased frequency or duration of hypopneas after the surgery. Here in 17 patients with AHI ≥ 60 events/h, having increased frequency or duration of hypopneas after the non-framework surgery, the results show that the surgery improved oxygen saturation by reducing obstructive-apnea index (36.1 events/h) and duration (8.6 s/event), despite it increased hypopnea index (16.8 events/h) and duration (9.8 s/event). The surgery improved the average of the mean oxyhemoglobin saturation of pulse oximetry (SpO2) by 2.8% (toward a ceiling mean of 94.3%), mean minimal SpO2 by 7.5%, and mean desaturation by 5%. The results suggest sufficient apnea reduction and shift from apnea to hypopnea may mask the negative impact of the increase of hypopnea index or duration and improve postoperative mean SpO2, minimal SpO2, and mean desaturation.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Individual product of (A) hypopnea index and mean hypopnea duration and (B) obstructive-apnea index and mean obstructive-apnea duration before and after the surgery. The surgery reduced the product on obstructive apnea but increased that on hypopnea.
Figure 2
Figure 2
Individual mean oxyhemoglobin saturation of pulse oximetry (SpO2) before and after the surgery.
Figure 3
Figure 3
Individual minimal oxyhemoglobin saturation of pulse oximetry (SpO2) before and after the surgery.
Figure 4
Figure 4
Individual mean desaturation before and after the surgery.
See this image and copyright information in PMC

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