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Editorial
. 2021 Feb;16(2):75-77.
doi: 10.2217/fvl-2020-0381. Epub 2021 Jan 20.

Can macrophages form a latent reservoir of HIV?

Victor Pham  1 , Matthew D Marsden  1   2
Affiliations
Editorial

Can macrophages form a latent reservoir of HIV?

Victor Pham et al. Future Virol. 2021 Feb.
No abstract available

Keywords: HIV; cure; in vivo; latency; macrophage; reservoir.

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Conflict of interest statement

Financial & competing interests disclosure The authors laboratory is supported by the National Institutes of Health Grant Number P01 AI131294 (Project 1). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.

References

    1. UNAIDS. UNAIDS 2020. Global Fact Sheet (2020). www.unaids.org/en/resources/fact-sheet
    1. Finzi D, Hermankova M, Pierson T et al. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278(5341), 1295–1300 (1997). - PubMed
    1. Chun TW, Stuyver L, Mizell SB et al. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc. Natl Acad. Sci. USA 94(24), 13193–13197 (1997). - PMC - PubMed
    1. Maldarelli F, Wu X, Su L et al. HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science 345(6193), 179–183 (2014). - PMC - PubMed
    1. Marsden MD, Zack JA. HIV cure strategies: a complex approach for a complicated viral reservoir? Future Virol. 14(1), 5–8 (2019).

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