Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Jan;34(120):67-70.
doi: 10.22038/IJORL.2021.54133.2847.

Laryngeal Myxoma: A rare localization

Malek Mnejja  1 , Imen Achour  1 , Wadii Thabet  1 , Rania Kharrat  1 , Rim Kallel  2 , Tahia Boudawara  2 , Bouthaina Hammami  1 , Ilhem Charfeddine  1
Affiliations
Case Reports

Laryngeal Myxoma: A rare localization

Malek Mnejja et al. Iran J Otorhinolaryngol. 2022 Jan.

Abstract

Introduction: Myxomas are benign mesenchymal neoplasms which arise mainly in the heart. The laryngeal localization is very rare. We aim to describe the clinical, histological and therapeutic features of this condition.

Case report: We report two cases of laryngeal myxomas occurred in male and female patients, presenting with a history of prolonged hoarseness. Laryngoscopy revealed a polypoid mass on the true vocal folds. The lesions were excised with cold instruments. One patient presented a recurrence 4 years after the first surgery.

Conclusions: Laryngeal myxoma should be considered in case of a benign looking vocal fold lesion, especially a vocal cord polyp. Histologic exam is the only tool to confirm the diagnosis. It is treated by surgical resection. In the literature, recurrence is rare in laryngeal site, but patients need to be kept on close follow-up.

Keywords: Larynx; Myxoma; Polyp; Vocal cord.

PubMed Disclaimer

Figures

Fig 1
Fig 1
Direct laryngoscopy shows polypoidal lesion on the right vocal cord (black arrow)
Fig 2
Fig 2
Excision of the lesion with cold instruments
Fig 3
Fig 3
A subepithelial paucicellular lesion, which formed by spindle to stellate cells within an abundant and hypovascular myxoid stroma (Hematoxylin and Eosin x 50)
See this image and copyright information in PMC

References

    1. Mesolella M, Petruzzi G, Salzano FA, Lamarca S, Cieri M, Russo D, et al. Multidisciplinary management of a giant and obstruc-tive laryngeal myxoma. Otorinolaringol. 2019;69:204–8.
    1. Panda S, Kumar R, Gopinath VR, Sagar P. Head and Neck Myxoma Presenting as Isolated Laryngeal Polyp. Case Rep Otolaryngol. 2018 - PMC - PubMed
    1. Imaizumi M, Tada Y, Tani A, Ikeda M, Nakaegawa Y, Omori K. Two Cases of Laryngeal Myxoma Misdiagnosed as a Vocal Fold Polyp. J Otol Rhinol. 2018;7
    1. Tang CG, Monin DL, Puligandla B, Cruz RM. Glottic myxoma presenting as chronic dysphonia: a case report and review of the literature. Ear Nose Throat J. 2015;94(1):E30–E33. - PubMed
    1. Ritchie A, Youngerman J, Fantasia JE, Kahn LB, Cocker RS. Laryngeal myxoma: a case report and review of the literature. Head Neck Pathol. 2014;8(2):204–8. - PMC - PubMed

Publication types

LinkOut - more resources