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. 2022 Jun;34(6):1357-1363.
doi: 10.1007/s40520-022-02077-0. Epub 2022 Feb 11.

Relationship between frailty, nutrition, body composition, quality of life, and gender in institutionalized older people

S K Jyväkorpi  1 , M Lindström  2 , M H Suominen  3 , H Kautiainen  3 , K Salminen  3 , R T Niskanen  3 , K H Pitkälä  3 , H-M Roitto  2
Affiliations

Relationship between frailty, nutrition, body composition, quality of life, and gender in institutionalized older people

S K Jyväkorpi et al. Aging Clin Exp Res. 2022 Jun.

Abstract

Our aim was to explore the relationship between frailty, nutrition, body composition, and how gender modifies this relationship among long-term care facility residents. We further investigated how body composition correlates with health-related quality of life (HRQoL) in both genders. In all, 549 residents (> 65 years of age) were recruited from 17 long-term care facilities for this cross-sectional study. Demographic information, diagnoses, use of medications, and nutritional supplements were retrieved from medical records. Participants' frailty status, cognition, nutritional status, HRQoL, and body composition were determined. Energy, protein, and fat intakes were retrieved from 1- to 2-day food diaries. The final sample consisted of 300 residents (77% women, mean age 83 years). The majority of participants, 62% of women and 63% of men, were identified as frail. Frail participants in both genders showed lower body mass index (p = 0.0013), muscle mass (MM) (p < 0.001), poorer nutritional status (p = 0.0012), cognition (p = 0.0021), and lower HRQoL (p < 0.001) than did prefrail participants. Women had higher fat mass, whereas men exhibited higher MM. The HRQoL correlated with the MM in both women, r = 0.48 [95% CI 0.38, 0.57] and men r = 0.49 [95% CI 0.38, 0.58]. Interventions aimed at strengthening and retaining MM of long-term residents may also support their HRQoL.

Keywords: Frailty; Gender; Health-related quality of life; Institutionalized older people; Muscle mass; Nutrition.

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Conflict of interest statement

The authors report no conflict of interest.

Figures

Fig. 1
Fig. 1
Correlation between muscle mass and health-related quality of life in women and men in institutionalized setting. CI confidence interval
See this image and copyright information in PMC

References

    1. Fried LP, Tangen CM, Walston J, Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) the Extended Group for EWGSOP2 et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;1:16–31.
    1. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146–M156. doi: 10.1093/gerona/56.3.M146. - DOI - PubMed
    1. Dent E, Morley JE, Cruz-Jentoft AJ, et al. Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management. J Nutr Health Aging. 2019;23:771–787. doi: 10.1007/s12603-019-1273-z. - DOI - PMC - PubMed
    1. Baum JL, Kim IY, Wolfe RR. Protein consumption and the elderly: what is the optimal level of intake? Nutrients. 2016;8:359. doi: 10.3390/nu8060359. - DOI - PMC - PubMed
    1. Daly RM, Nowson CA. Can protein supplementation lead to clinically meaningful improvements in muscle mass and function in undernourished (pre)frail elderly? Am J Clin Nutr. 2018;108:911–912. doi: 10.1093/ajcn/nqy289. - DOI - PubMed

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