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Clinical Trial
. 1986 Mar;26(3):211-4.
doi: 10.1002/j.1552-4604.1986.tb02936.x.

Treatment of depression in chronic cocaine and phencyclidine abuse with desipramine

A J Giannini, D A Malone, M C Giannini, W A Price, R H Loiselle
Clinical Trial

Treatment of depression in chronic cocaine and phencyclidine abuse with desipramine

A J Giannini et al. J Clin Pharmacol. 1986 Mar.

Abstract

An open field trial was conducted comparing desipramine and an active placebo in separate populations of chronic cocaine and phencyclidine (PCP) abusers, who discontinued their abuse. Subjects who received desipramine showed a decrease in depressive symptoms after a 20-40 day period regardless of whether they abused PCP or cocaine.

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