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Editorial
. 2022 Apr 15;205(8):862-864.
doi: 10.1164/rccm.202201-0086ED.

Hypoxia Can Make Neutrophils Hyper, Potentially Wreaking Havoc during Exacerbations in Chronic Obstructive Pulmonary Disease

John C Gomez  1   2 , Claire M Doerschuk  1   2
Affiliations
Editorial

Hypoxia Can Make Neutrophils Hyper, Potentially Wreaking Havoc during Exacerbations in Chronic Obstructive Pulmonary Disease

John C Gomez et al. Am J Respir Crit Care Med. .
No abstract available

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References

    1. Jantsch J, Schödel J. Hypoxia and hypoxia-inducible factors in myeloid cell-driven host defense and tissue homeostasis. Immunobiology . 2015;220:305–314. - PubMed
    1. Lodge KM, Cowburn AS, Li W, Condliffe AM. The impact of hypoxia on neutrophil degranulation and consequences for the host. Int J Mol Sci . 2020;21:1183–1204. - PMC - PubMed
    1. Wong BW, Marsch E, Treps L, Baes M, Carmeliet P. Endothelial cell metabolism in health and disease: impact of hypoxia. EMBO J . 2017;36:2187–2203. - PMC - PubMed
    1. Lodge KM, Vassallo A, Liu B, Long M, Tong Z, Newby PR, et al. Hypoxia increases the potential for neutrophil-mediated endothelial damage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med . 2022;205:903–916. - PMC - PubMed
    1. Perkel JM. Single-cell proteomics takes centre stage. Nature . 2021;597:580–582. - PubMed