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. 2022 Jun;94(6):2360-2364.
doi: 10.1002/jmv.27659. Epub 2022 Feb 21.

Omicron BA.2 lineage spreads in clusters and is concentrated in Denmark

Perumal A Desingu  1 , K Nagarajan  2
Affiliations

Omicron BA.2 lineage spreads in clusters and is concentrated in Denmark

Perumal A Desingu et al. J Med Virol. 2022 Jun.
No abstract available

Keywords: BA.1 lineage; BA.2 lineage; BA.3 lineage; Omicron variant; SARS-CoV-2.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Genetic diversity in the Omicron variant. (A) Phylogenetic tree depicting the relationship and substitution rate of different lineages of Omicron variant. This Phylogenetic tree was created using the Nextstrain online tool, with options such as nCoV, GISAID sequences, global sequences, PANGO Lineage, and CLOCK tree in this online tool for the Omicron variant (https://www.gisaid.org/phylodynamics/global/nextstrain/, January 14, 2022). (B and C) Depicting the part of Omicron variant's different lineages sequences detected in Denmark against Worldwide (as of January 18, 2022, sequences submitted in GISAID); (B) represent BA.2 lineage; (C) represent BA.1 lineage, and (D) represent B.1.1.529 lineage. (E) Phylogenetic tree displaying the presence of five different subgroups in the BA.2 lineage and their specific mutations. This Phylogenetic tree was created using the Nextstrain online tool, with options such as nCoV, GISAID sequences, global sequences, PANGO Lineage, and Rectangular tree in this online tool for the Omicron variant (https://www.gisn/aid.org/phylodynamics/global/nextstrai, January 14, 2022)
Figure 2
Figure 2
The five subgroups with the BA.2 lineage express different and distinct mutations in different geographical regions. (A and B) Depicting the expression of a specific mutation in the ORF1a: A2909V and ORF3a: L140F in the Philippines and Hong Kong subgroups and its global distribution, as well as numbers sequences, has this mutation in the BA.2 lineage; (A) represent ORF1a: A2909V mutation, and (B) represent ORF3a: L140F mutation. This information is derived from the online tool “SARS‐CoV‐2 (hCoV‐19) Mutation Reports” (https://outbreak.info/compare-lineages, January 18, 2022). (C and D) Depicting the expression of a specific mutation in the ORF1a: −3677L and ORF1b: S959P in the Indian subgroup and its global distribution and numbers sequences have this mutation in the BA.2 lineage. (C) represent ORF1a: −3677L mutation, and (D) represent ORF1b: S959P mutation. This information is derived from the online tool “SARS‐CoV‐2 (hCoV‐19) Mutation Reports” (E) Depicting the expression of a specific mutation in the ORF3a: H78Y in the Sweden/Denmark subgroup and its global distribution and numbers sequences have this mutation in the BA.2 lineage. This information is derived from the online tool “SARS‐CoV‐2 (hCoV‐19) Mutation Reports” (https://outbreak.info/compare-lineages, January 18, 2022). (F) Phylogenetic tree depicting the presence of ORF3a: H78Y mutation in the BA.2 sequences submitted from Denmark. This Phylogenetic tree was created using the Nextstrain online tool, with options such as nCoV, GISAID sequences, Denmark sequences, PANGO Lineage, and Rectangular tree in this online tool for the Omicron variant (https://www.gisaid.org/phylodynamics/denmark/, January 14, 2022)
See this image and copyright information in PMC

References

    1. Desingu PA, Nagarajan K, Dhama K. Emergence of Omicron third lineage BA.3 and its importance. J Med Virol. 2022. 10.1002/jmv.27601 - DOI - PMC - PubMed
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    1. Desingu PA, Nagarajan K, Dhama K. Emergence of Omicron third lineage BA.3 and its importance. J Med Virol. 2022. 10.1002/jmv.27601 - DOI - PMC - PubMed
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