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. 2022 Apr;29(4):298-301.
doi: 10.1111/jvh.13657. Epub 2022 Feb 20.

Quantitative HBsAg an unreliable marker for diagnosis and disease progression in genotype F chronic HBeAg-negative infections

Hugo Fainboim  1 , Nicolas Di Benedetto  2 , Silvia Paz  1 , Manuel Mendizabal  3 , Soledad Campuzano  1 , Mercedes Elizalde  4   5 , Luciana Tadey  6 , Gabriel Deluchi  6 , María Belén Bouzas  6 , Lilia Mammana  6 , Diego Flichman  4   5
Affiliations

Quantitative HBsAg an unreliable marker for diagnosis and disease progression in genotype F chronic HBeAg-negative infections

Hugo Fainboim et al. J Viral Hepat. 2022 Apr.
No abstract available

Keywords: HBV-DNA; biomarkers; hepatitis B virus; liver disease; pathogenesis.

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References

REFERENCES

    1. Likhitsup A, Lok AS. Understanding the natural history of hepatitis B virus infection and the new definitions of cure and the endpoints of clinical trials. Clin Liver Dis. 2019;23:401-416.
    1. European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu; European Association for the Study of the Liver. EASL 2017 clinical practice guidelines on the management of hepatitis B virus infection. J Hepatol. 2017;2017(67):370-398.
    1. Cornberg M, Wong VW, Locarnini S, Brunetto M, Janssen HLA, Chan HL. The role of quantitative hepatitis B surface antigen revisited. J Hepatol. 2017;66:398-411.
    1. Kuhnhenn L, Jiang B, Kubesch A, et al. Impact of HBV genotype and mutations on HBV DNA and qHBsAg levels in patients with HBeAg-negative chronic HBV infection. Aliment Pharmacol Ther. 2018;47:1523-1535.
    1. Liu J, Yang HI, Lee MH, et al. Serum levels of hepatitis B surface antigen and DNA can predict inactive carriers with low risk of disease progression. Hepatology. 2016;64:381-389.

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