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Comparative Study
. 1986 Mar 11;14(5):2201-13.
doi: 10.1093/nar/14.5.2201.

The isolation and nucleotide sequence of the complex AROM locus of Aspergillus nidulans

I G Charles, J W Keyte, W J Brammar, M Smith, A R Hawkins
Free PMC article
Comparative Study

The isolation and nucleotide sequence of the complex AROM locus of Aspergillus nidulans

I G Charles et al. Nucleic Acids Res. .
Free PMC article

Abstract

The AROM locus of A. nidulans, which governs five consecutive steps in pre-chorismate aromatic amino acid biosynthesis, has been cloned in a bacteriophage vector. The nucleotide sequence of the locus reveals a single, open reading-frame of 4,812 base-pairs, apparently without introns. An internal segment of the A. nidulans AROM sequence has extensive homology with the E. coli aroA gene that encodes the 5-enolpyruvylshikimate 3-phosphate synthase.

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