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Case Reports
. 2021 Sep-Dec;12(3):414-417.
doi: 10.4103/njms.NJMS_227_20. Epub 2021 Dec 13.

Treatment of a central giant cell lesion in the mandible

Bernardo Correia Lima  1 , Giulianna Lima Pinheiro  1 , Leonardo Augustus Peral Ferreira Pinto  1 , Maria Aparecida de Albuquerque Cavalcante  1
Affiliations
Case Reports

Treatment of a central giant cell lesion in the mandible

Bernardo Correia Lima et al. Natl J Maxillofac Surg. 2021 Sep-Dec.

Abstract

Central giant cell lesion (CGCL) is a benign intraosseous lesion that usually accompany the gnathic bones in the anterior region, mostly crossing the midline. Its clinical features involve cortical expansion, tooth displacement, and root resorption. Pain may occur in 20% of cases. Histopathological characteristics are like other pathological entities, being necessary discarding them. In this case, a 53-year-old female presented an expansive legion in the anterior mandible with tooth displacement and pain. After incisional biopsy, the result was CGCL. Surgical planning involved manufacturing a biomodel, bending the reconstruction plate to give the correct mandibular arch perimeter. After that, it was performed a segmental resection and installation of a reconstruction plate using a cervical approach. The patient is under follow-up with no signs of recurrence or complications.

Keywords: Aggressive; benign bone lesions; central giant cell lesion; mandible.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Frontal view of the patient. Note the mandibular asymmetry in the anterior region
Figure 2
Figure 2
Intraoral view of the lesion. Note the poor periodontal health of the patient and the size of the lesion
Figure 3
Figure 3
Panoramic reconstruction from cone-beam computed tomography showing the complete destruction of the mandibular basilar
Figure 4
Figure 4
Reconstruction plate reestablishing the mandibular arch perimeter
Figure 5
Figure 5
Mandible ressected with the central giant cell lesion
Figure 6
Figure 6
Postoperative panoramic radiography showing the mandibular perimeter arch preserved and the good position of the reconstruction plate
See this image and copyright information in PMC

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