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Case Reports
. 2022 Jan 22;6(2):152-154.
doi: 10.1002/jgh3.12711. eCollection 2022 Feb.

Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo-luminal tissue diagnosis

Choon-Seng Qua  1 , Kaik-Boo Peh  2 , Saravannan Kannan  3 , Khean-Lee Goh  4
Affiliations
Case Reports

Retroperitoneal extragonadal germ cell tumor with duodenal infiltration: A challenging endo-luminal tissue diagnosis

Choon-Seng Qua et al. JGH Open. .

Abstract

A 32-year-old Malay male was referred to our hospital for a second opinion. An abdominal and pelvic CT scan at the previous medical facility showed a large retroperitoneal tumor, which was subjected to ultrasound-guided fine-needle aspiration cytology (FNAC) with a provisional diagnosis of malignant lymphoma. However, after reviewing the existing results, a repeat biopsy was deemed necessary and this was performed endoluminally via gastroduodenoscopy in view of the close proximity of the tumor and the third part of the duodenum. The first biopsy failed to detect any abnormal cells, but a repeat biopsy with supporting evidence from other laboratory results led to a final diagnosis of extragonadal germ cell tumor (GCT) with duodenal infiltration.

Keywords: germ cell tumor; retroperitoneal tumor; ultrasound‐guided fine‐needle aspiration cytology.

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Figures

Figure 1
Figure 1
Retroperitoneal soft tissue mass abutting D3.
Figure 2
Figure 2
Retroperitoneal soft tissue mass encasing inferior vena cava and abutting D3.
Figure 3
Figure 3
Ulcerated nodular lesion in D3.
Figure 4
Figure 4
Histology of the biopsy showing immature glands and stroma, white arrows indicate spindle shaped cells. H&E stain, ×100.
See this image and copyright information in PMC

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