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. 2022 Apr;101(4):824-825.
doi: 10.1016/j.kint.2022.01.016. Epub 2022 Feb 12.

Breakthrough omicron COVID-19 infections in patients receiving the REGEN-Cov antibody combination

Affiliations

Breakthrough omicron COVID-19 infections in patients receiving the REGEN-Cov antibody combination

Adrien Flahault et al. Kidney Int. 2022 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Occurrence of coronavirus disease 2019 (COVID-19) breakthrough infections is associated with the occurrence of the Omicron variant in Ile-de-France, France. Green dashed line: cumulative number of REGEN-Cov administrations. Red line: cumulative number of COVID-19 infections among patients treated with REGEN-Cov in our cohort. Black curve: COVID-19 incidence rate in Ile de France, France, per 100,000 inhabitants. Blue area: proportion of COVID-19 cases with the suspected Delta variant (the presence of the L452R mutation) in Ile-de-France, France. Pink area: proportion of COVID-19 cases with suspected Omicron variant (the lack of the L452R mutation) in Ile-de-France, France. Data for Ile de France were obtained from Santé Publique France (https://geodes.santepubliquefrance.fr) on January 22, 2022.

References

    1. Ducloux D., Courivaud C. REGEN-Cov antibody combination to prevent COVID-19 infection in kidney transplant recipient without detectable antibody response to optimal vaccine scheme. Kidney Int. 2022;101:645–646. - PMC - PubMed
    1. O’Brien M.P., Forleo-Neto E., Musser B.J., et al. Subcutaneous REGEN-COV antibody combination to prevent Covid-19. N Engl J Med. 2021;385:1184–1195. - PMC - PubMed
    1. Planas D., Saunders N., Maes P., et al. Considerable escape of SARS-CoV-2 Omicron to antibody neutralization. Nature. 2022;602:671–675. - PubMed
    1. Wilhelm A., Widera M., Grikscheit K., et al. Reduced neutralization of SARS-CoV-2 Omicron variant by vaccine sera and monoclonal antibodies. medRxiv. https://doi.org/10.1101/2021.12.07.21267432 Published online December 8, 2021. - DOI

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