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. 1979 Jan 15;178(1):103-7.
doi: 10.1042/bj1780103.

Artificially induced active transport of amino acid driven by the efflux of a sugar via a heterologous transport system in de-energized Escherichia coli

M Bentaboulet, A Robin, A Kepes

Artificially induced active transport of amino acid driven by the efflux of a sugar via a heterologous transport system in de-energized Escherichia coli

M Bentaboulet et al. Biochem J. .

Abstract

Consistent with the model of an H+ cotransport, amino acid uptake can be driven by a proton gradient generated by an efflux of sugar when the normal energy sources are suppressed. Heterologous countertransport is completely inhibited by uncouplers unlike homologous countertransport. Positive coupling was obtained with methyl thiogalactoside/proline, methyl thiogalactoside/phenylalanine, gluconate/proline; however, the poor coupling efficiency suggests a more complex sequence of reactions.

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References

    1. J Biol Chem. 1975 Feb 25;250(4):1405-12 - PubMed
    1. Biochim Biophys Acta. 1975 Sep 16;406(1):50-9 - PubMed
    1. Ann Inst Pasteur (Paris). 1956 Dec;91(6):829-57 - PubMed
    1. J Membr Biol. 1977 Mar 8;31(3):233-55 - PubMed
    1. Biochemistry. 1975 Dec 16;14(25):5451-61 - PubMed

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