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. 2022 Jan 24;19(3):1302.
doi: 10.3390/ijerph19031302.

Direct Comparison of Elastography Endoscopic Ultrasound Fine-Needle Aspiration and B-Mode Endoscopic Ultrasound Fine-Needle Aspiration in Diagnosing Solid Pancreatic Lesions

Marcel Gheorghiu  1 , Zeno Sparchez  1   2 , Ioana Rusu  1   2 , Sorana D Bolboacă  3 , Radu Seicean  4 , Cristina Pojoga  2   5 , Andrada Seicean  1   2
Affiliations

Direct Comparison of Elastography Endoscopic Ultrasound Fine-Needle Aspiration and B-Mode Endoscopic Ultrasound Fine-Needle Aspiration in Diagnosing Solid Pancreatic Lesions

Marcel Gheorghiu et al. Int J Environ Res Public Health. .

Abstract

Elastography endoscopic ultrasound (E-EUS) has been proved to be a valuable supplement to endoscopic ultrasound fine-needle aspiration (EUS-FNA) in differentiating solid pancreatic lesions, but the improvement of EUS-FNA guided during E-EUS has not been proven. Our study aimed to evaluate whether E-EUS fine-needle aspiration (E-EUS-FNA) was superior to B-mode EUS-FNA for the diagnosis of solid pancreatic masses and whether the diagnostic rate was affected by specific factors. Our prospective study was conducted between 2019-2020 by recruiting patients with solid pancreatic masses. E-EUS examination was followed by one pass of E-EUS-FNA towards the blue part of the lesion and a second pass of EUS-FNA. The final diagnosis was based on surgery, E-EUS-FNA or EUS-FNA results, or a 12-month follow-up. Sixty patients with solid pancreatic lesions were evaluated. The sensitivity, specificity, and accuracy for diagnosing malignancy using E-EUS-FNA and EUS-FNA were 89.5%, 100%, 90%, 93%, 100%, and 93.3%, respectively, but the differences were not significant. Neither mass location nor the lesion size influenced the results. The lengths of the core obtained during E-EUS-FNA and EUS-FNA were similar. E-EUS-FNA in solid pancreatic lesions was not superior to B-mode EUS-FNA.

Keywords: EUS-FNA (endoscopic ultrasound fine-needle aspiration); diagnostic; elastography; endoscopic ultrasound (EUS); fine needle aspiration (FNA); histology; pancreatic cancer.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Elastography endoscopic ultrasound fine-needle aspiration of pancreatic adenocarcinoma.
Figure 2
Figure 2
Elastography endoscopic ultrasound fine-needle aspiration from a pancreatic neuroendocrine tumor.
See this image and copyright information in PMC

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