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Randomized Controlled Trial
. 2022 Feb 2;19(3):1738.
doi: 10.3390/ijerph19031738.

'Physio-EndEA' Study: A Randomized, Parallel-Group Controlled Trial to Evaluate the Effect of a Supervised and Adapted Therapeutic Exercise Program to Improve Quality of Life in Symptomatic Women Diagnosed with Endometriosis

María Del Mar Salinas-Asensio  1   2   3 , Olga Ocón-Hernández  2   4 , Antonio Mundo-López  5 , Carolina Fernández-Lao  1   2   3 , Francisco M Peinado  2 , Carmen Padilla-Vinuesa  2   4 , Francisco Álvarez-Salvago  6 , Paula Postigo-Martín  1   2   3 , Mario Lozano-Lozano  1   2   3 , Ana Lara-Ramos  7 , Manuel Arroyo-Morales  1   2   3 , Irene Cantarero-Villanueva  1   2   3 , Francisco Artacho-Cordón  2   3   8   9
Affiliations
Randomized Controlled Trial

'Physio-EndEA' Study: A Randomized, Parallel-Group Controlled Trial to Evaluate the Effect of a Supervised and Adapted Therapeutic Exercise Program to Improve Quality of Life in Symptomatic Women Diagnosed with Endometriosis

María Del Mar Salinas-Asensio et al. Int J Environ Res Public Health. .

Abstract

Aim: The 'Physio-EndEA' study aims to explore the potential benefits of a therapeutic exercise program (focused on lumbopelvic stabilization and tolerance to exertion) on the health-related quality of life (HRQoL) of symptomatic endometriosis women.

Design: The present study will use a parallel-group randomized controlled trial design.

Methods: A total of 22 symptomatic endometriosis women will be randomized 1:1 to the Physio-EndEA or usual care groups. The 'Physio-EndEA' program will consist of a one-week lumbopelvic stabilization learning phase followed by an eight-week phase of stretching, aerobic and resistance exercises focused on the lumbopelvic area that will be sequentially instructed and supervised by a trained physiotherapist (with volume and intensity progression) and adapted daily to the potential of each participant. The primary outcome measure is HRQoL. The secondary outcome measures included clinician-reported outcomes (pressure pain thresholds, muscle thickness and strength, flexibility, body balance and cardiorespiratory fitness) and patient-reported outcomes (pain intensity, physical fitness, chronic fatigue, sexual function, gastrointestinal function and sleep quality).

Discussion: Findings of this study will help to identify cost-effective non-pharmacological options (such as this exercise-based intervention) that may contribute to the improvement of HRQoL in symptomatic endometriosis women.

Keywords: endometriosis; motor control; pain; physiotherapy; quality of life; therapeutic exercise.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flow diagram of participant recruitment during the trial according to SPIRIT.
See this image and copyright information in PMC

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