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. 2022 Feb 5;19(3):1803.
doi: 10.3390/ijerph19031803.

Effect of Antioxidant Supplementation on Markers of Oxidative Stress and Muscle Damage after Strength Exercise: A Systematic Review

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Effect of Antioxidant Supplementation on Markers of Oxidative Stress and Muscle Damage after Strength Exercise: A Systematic Review

Cristina Canals-Garzón et al. Int J Environ Res Public Health. .

Abstract

Background: The purpose of this systematic review was to determine the effect of antioxidant consumption on markers of oxidative stress and muscle damage after performing a muscle strength exercise.

Methods: The Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statements were followed. Four databases were used: Scopus, PubMed, WOS and SportDiscus. Methodological quality was assessed using the PEDro scale.

Results: A total of 1709 articles were retrieved and following duplicate removal and application of exclusion criteria seven articles were reviewed. Supplementation with pomegranate juice alleviates oxidative stress, taurine reduces muscle damage, melatonin protects the skeletal muscles, blueberries decrease oxidation and oats mitigate muscle damage.

Conclusions: Acute administration of antioxidants immediately before or during an exercise session can have beneficial effects, such as delay of fatigue and a reduction in the recovery period. Administration of antioxidant susbtances may reduce muscle damage and oxidative stress markers.

Keywords: antioxidants; free radicals; muscle damage; oxidative stress; strength training.

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
PRISMA flow diagram of the selection process of articles included in the systematic literature review of investigating the effect of antioxidant supplementation after a strength exercise.

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References

    1. Gomez M.C., Carretero A., Millan-Domingo F., Garcia E., Correas A., Olaso G., Viña J. Redox-related biomarkers in physical exercise. Redox Biol. 2021;42:101956. doi: 10.1016/j.redox.2021.101956. - DOI - PMC - PubMed
    1. Diaz-Castro J., Moreno-Fernandez J., Chirosa I., Chirosa L.J., Guisado R., Ochoa J.J. Beneficial effect of ubiquinol on hematological and inflammatory signaling during exercise. Nutrients. 2020;12:424. doi: 10.3390/nu12020424. - DOI - PMC - PubMed
    1. Piercy K.L., Troiano R.P., Ballard R.M., Carlson S.A., Fulton J.E., Galuska D.A., George S.M., Olson R.D. The physical activity guidelines for Americans. JAMA. 2018;320:2020–2028. doi: 10.1001/jama.2018.14854. - DOI - PMC - PubMed
    1. Simon H.B. Exercise and health: Dose and response, considering both ends of the curve. Am. J. Med. 2015;128:1171–1177. doi: 10.1016/j.amjmed.2015.05.012. - DOI - PubMed
    1. Hernández M.C., Pascual A.L.C. Benefits of physical exercise in healthy population and impact on the appearance of disease. Endocrinol. Nutr. 2013;60:283–286. - PubMed

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