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. 2022 Feb 15;28(1):5.
doi: 10.1186/s40885-021-00187-x.

Correlation between short-term blood pressure variability parameters with mobil-O-graph pulse wave velocity

Marco Antonio Vieira Silva  1   2 , Luiz Antonio Pertilli Rodrigues Resende  3   4 , Mateus Marchiori Vieira  5 , Camila Blanco Ferreira Jajah  6 , Lucas Alves Berzotti  6 , Nicole Cristine Rambourg  6 , Ian Dias de Souza Pierson  6 , João Lucas Carvalho Achkar  6 , Livia Marchiori Vieira  7 , Guilherme Marchiori Moreira  8 , Geisa Ribeiro Borges  9 , Dalmo Correia  3   4
Affiliations

Correlation between short-term blood pressure variability parameters with mobil-O-graph pulse wave velocity

Marco Antonio Vieira Silva et al. Clin Hypertens. .

Abstract

Background: Blood pressure variability (BPV) and arterial stiffness show an association with increased cardiovascular events. Evidences demonstrated an association between higher short-term systolic BPV and stiffer arteries. There is no previous study assessed the correlation between BPV and arterial stiffness measured by a Mobil-O-Graph device. We issued to evaluate the correlation between short-term BPV parameters and Mobil-O-Graph pulse wave velocity (PWV) among suspected hypertensive individuals under treatment.

Methods: Mobil-O-Graph device estimated arterial stiffness (oscillometric PWV [oPWV]) in 649 individuals, and they recorded 24-h ambulatory BP; 428 had suspected hypertension and 221 under treatment. We analyzed the correlation between oPWV and measures of BPV: SD of 24 h BP (24-h SD), SD of daytime BP (daytime-SD), and SD of nighttime BP (nighttime-SD), weighted SD of 24-h BP (wSD), coefficient of variation of 24-h BP (CV 24-h) and average real variability (ARV).

Results: Oscillometric PWV showed a positive correlation with all systolic BPV measures, in both groups. Among suspected hypertensives: 24-h SD, r = 0.30; SD daytime-SD, r = 0.34; nighttime-SD, r = 0.16; wSD, r = 0.30; CV 24-h, r = 0.24; ARV, r = 0.22. In the treated individuals: 24-h SD, r = 0.46; daytime-SD, r = 0.47; nighttime-SD, r = 0.35; wSD, r = 0.50; CV 24-h, r = 0.43; ARV, r = 0.37, all P < 0.001. Diastolic BPV demonstrated association with some measures of BPV. In suspected hypertensive group: nighttime-SD, r = 0.13; wSD, r = 0.10, both P < 0.001. And in treated individuals: daytime-SD, r = 0.23; wSD, r = 0.22; CV 24-h, r = 0.19 (all P < 0.001), ARV, r = 0.15 (P < 0.05). Systolic daytime-SD in suspected and diastolic CV 24-h in treated group independently predicted oPWV.

Conclusion: We observed a positive and independent correlation between Mobil-O-Graph pulse wave velocity and BPV measures, strong to systolic BPV and weak to diastolic BP.

Keywords: Ambulatory blood pressure monitoring; Arterial stiffness; Hypertension; Pulse wave velocity; Short term blood pressure variability.

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Conflict of interest statement

The authors declare that they have no competing interests in this section.

Figures

Fig. 1
Fig. 1
Scatter diagram of a correlation between systolic daytime-SD in suspected hypertensives (A) and weighted SD of systolic 24 hours BP in treated hypertensives (B) with Mobil-O-Graph PWV BP, blood pressure; PWV, pulse wave velocity; r, Pearson correlation coefficient; SD, standard deviation
Fig. 2
Fig. 2
Scatter diagram of a correlation between of weighted SD of diastolic 24 hours BP in suspected hypertensives (A) and diastolic daytime-SD in treated hypertensives (B) with Mobil-O-Graph PWV BP, blood pressure; PWV, pulse wave velocity; r, Pearson correlation coefficient; SD, standard deviation
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