Trimethoprim-sulfamethoxazole resistance patterns among Staphylococcus aureus in the United States, 2012-2018
- PMID: 35166197
- PMCID: PMC10150455
- DOI: 10.1017/ice.2022.9
Trimethoprim-sulfamethoxazole resistance patterns among Staphylococcus aureus in the United States, 2012-2018
Abstract
We reviewed trimethoprim-sulfamethoxazole antibiotic susceptibility testing data among Staphylococcus aureus using 3 national inpatient databases. In all 3 databases, we observed an increases in the percentage of methicillin-resistant Staphylococcus aureus that were not susceptible to trimethoprim-sulfamethoxazole. Providers should select antibiotic regimens based on local resistance patterns and should report changes to the public health department.
Conflict of interest statement
References
-
- Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis 2014;59: e10–e52. - PubMed
-
- US Department of Health and Human Services. Antibiotic resistance threats in the United States, 2019. Centers for Disease Control and Prevention website. https://www.cdc.gov/drugresistance/pdf/threats-report/2019-ar-threats-re.... Published 2019. Accessed January 24, 2022.
-
- Storandt MH, Walden CD, Sahmoun AE, Beal JR. Trends and risk factors in the antibiotic management of skin and soft-tissue infections in the United States. J Dermatolog Treat 2021;28:1–5. - PubMed
-
- Nurjadi D, Olalekan AO, Layer F, et al. Emergence of trimethoprim resistance gene dfrG in Staphylococcus aureus causing human infection and colonization in sub-Saharan Africa and its import to Europe. J Antimicrob Chemother 2014;69:2361–2368. - PubMed
-
- Nurjadi D, Fleck R, Lindner A, et al. Import of community-associated, methicillin-resistant Staphylococcus aureus to Europe through skin and soft-tissue infection in intercontinental travellers, 2011–2016. Clin Microbiol Infect 2019;25:739–746. - PubMed
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