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. 2022 Jul;46(7):1561-1566.
doi: 10.1007/s00268-022-06466-4. Epub 2022 Feb 15.

Esophageal Achalasia: Evaluation and Treatment of Recurrent Symptoms

Marco G Patti  1 , Francisco Schlottmann  2   3 , Fernando A M Herbella  4
Affiliations

Esophageal Achalasia: Evaluation and Treatment of Recurrent Symptoms

Marco G Patti et al. World J Surg. 2022 Jul.

Abstract

Background: Esophageal achalasia is a primary esophageal motility disorder of unknown origin. Treatment is palliative and its goal is to decrease the resistance posed by a non-relaxing and often hypertensive lower esophageal sphincter. This goal can be accomplished by different treatment modalities such as pneumatic dilatation, laparoscopic myotomy or peroral endoscopic myotomy. In some patients, however, symptoms tend to recur overtime.

Methods: A comprehensive literature search was performed on PubMed focused on the management of recurrent achalasia.

Results: The available treatment modalities can be used, alone or in combination. The goal of treatment is to resolve/improve symptoms, avoiding an esophagectomy, an operation linked to significant morbidity.

Conclusions: The treatment of these patients is often very challenging, and the best results are obtained in centers where a multidisciplinary team-radiologists, gastroenterologists, and surgeons-is present.

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References

    1. Fisichella PM, Raz D, Palazzo F et al (2008) Clinical, radiological, and manometric profile in 145 patients with untreated achalasia. World J Surg 32:1974–1979. https://doi.org/10.1007/s00268-008-9656-z - DOI - PubMed
    1. Inoue H, Minami H, Kobayashi Y et al (2010) Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy 42:265–271 - DOI - PubMed
    1. Boeckxstaens GE, Annese V, des Varannes SB et al (2011) Pneumatic dilation versus laparoscopic Heller’s myotomy for idiopathic achalasia. European Achalasia Trial Investigators. N Engl J Med 364:1807–1816 - DOI - PubMed
    1. Familiari P, Gigante G, Marchese M et al (2016) Peroral endoscopic myotomy for esophageal achalasia: outcomes of the first 100 patients with short-term follow-up. Ann Surg 263:82–87 - DOI - PubMed
    1. Schlottmann F, Luckett DJ, Fine J et al (2018) Laparoscopic Heller myotomy versus peroral endoscopic myotomy (POEM) for achalasia. A systematic review and meta-analysis. Ann Surg 267:451–460 - DOI - PubMed

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