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Review
. 2022 Apr;24(4):53-63.
doi: 10.1007/s11894-022-00837-6.

Sarcopenia in Chronic Pancreatitis - Prevalence, Diagnosis, Mechanisms and Potential Therapies

Matthew Fasullo  1 , Endashaw Omer  2 , Matthew Kaspar  3
Affiliations
Review

Sarcopenia in Chronic Pancreatitis - Prevalence, Diagnosis, Mechanisms and Potential Therapies

Matthew Fasullo et al. Curr Gastroenterol Rep. 2022 Apr.

Abstract

Purpose of review: To investigate the prevalence, pathogenesis, diagnosis, clinical sequelae, and management of sarcopenia to improve mortality and quality of life in those with Chronic Pancreatitis.

Recent findings: Sarcopenia is prevalent in chronic pancreatitis and can significantly affect clinical outcomes. Sarcopenia is prevalent in chronic pancreatitis. While effects on some clinical outcomes is has been shown, there is a significant gap in knowledge regarding effects on outcomes, pathophysiology, and options for management.

Keywords: Chronic pancreatitis; Malnutrition; Pancreatitis; Sarcopenia.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance
    1. Muniraj T, Aslanian HR, Farrell J, et al. Chronic pancreatitis, a comprehensive review and update. Part I: epidemiology, etiology, risk factors, genetics, pathophysiology, and clinical features. 2014;60(12):530–50. https://doi.org/10.1016/j.disamonth.2014.11.002 . - DOI
    1. Singh VK, Yadav D, Garg PK. Diagnosis and Management of Chronic Pancreatitis: A Review. JAMA. 2019 Dec 24;322(24):2422-2434. https://doi.org/10.1001/jama.2019.19411 . An excellent review of diagnosis & management of chronic pancreatitis.
    1. Whitcomb DC, Frulloni L, Garg P, Greer JB, Schneider A, Yadav D, Shimosegawa T. Chronic pancreatitis: An international draft consensus proposal for a new mechanistic definition. Pancreatology. 2016 Mar-Apr;16(2):218–24. https://doi.org/10.1016/j.pan.2016.02.001 . Consensus statement on classification of etiologies of chronic pancreatitis by proposed mechanism.
    1. Majumder S, Chari ST. Chronic pancreatitis. 2016;387(10031):1957–66. https://doi.org/10.1016/S0140-6736(16)00097-0 . - DOI
    1. Whitcomb DC. Mechanisms of disease: Advances in understanding the mechanisms leading to chronic pancreatitis. Nat Clin Pract Gastroenterol Hepatol. 2004 Nov;1(1):46–52. https://doi.org/10.1038/ncpgasthep0025 . - DOI - PubMed

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