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. 1986 May;52(2):609-12.
doi: 10.1128/iai.52.2.609-612.1986.

Homologous regions within M protein genes in group A streptococci of different serotypes

J R Scott, S K Hollingshead, V A Fischetti

Homologous regions within M protein genes in group A streptococci of different serotypes

J R Scott et al. Infect Immun. 1986 May.

Abstract

DNA hybridization with probes from the structural gene for the M6 protein shows that the carboxy-terminal region (proximal to the cell surface) is conserved among strains of different M serotypes. The amino-terminal region, which is more available to immunological surveillance, exhibits greater variation.

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