Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Feb 3;17(4):1068-1075.
doi: 10.1016/j.radcr.2022.01.049. eCollection 2022 Apr.

MRI aspects of left ventricular non compaction (LVNC): About 3 cases from Sub-Saharan Africa and review of the literature

Affiliations
Case Reports

MRI aspects of left ventricular non compaction (LVNC): About 3 cases from Sub-Saharan Africa and review of the literature

Abdoulaye Toure et al. Radiol Case Rep. .

Erratum in

Abstract

Left ventricular non compaction (LVNC) is a relatively rare variety of cardiomyopathy of genetic origin. We report three cases of LVNC diagnosed on cardiac magnetic resonance imaging (MRI) in Abidjan in patients aged 42, 46 and 60 years, referred for suspected LVNC on echocardiography. We used a 1.5 T MRI and performed the following sequences: black blood and white blood, LV minor axis, LV major axis, 4 cavities, and T1 SPIR Gadolinium (early and late enhancement at 10 minutes). MRI made the diagnosis of LVNC based on a double-layered myocardium, the inner (endocardium) non compacted, fibrillar thickened and the outer (epicardium) compacted thin with a non compacted to compacted myocardium ratio greater than 2.3, making the formal diagnosis. Cardiac MRI is an excellent diagnostic tool for LVNC. Its recent use in Africa should be common in the management of this cardiomyopathy.

Keywords: Abidjan; Left ventricular non compaction cardiomyopathy; MRI.

PubMed Disclaimer

Figures

Fig 1
Fig. 1
Cardiac magnetic resonance imaging (MRI) T2 sequence; four-cavity slice horizontal long axe (HLA); Hypertrophy of the endocardium with the endocardium/epicardium ratio estimated at 3.49.
Fig 2
Fig. 2
Cardiac magnetic resonance imaging (MRI) T2 sequence; short axis section of the heart passing through the apex of the left ventricle. Cryptic hypertrophy of the endocardium (white arrow).
Fig 3
Fig. 3
Cardiac magnetic resonance imaging (MRI) T2 sequence, Four-cavity section (HLA), Situs inversus with dextrocardia; The endocardium/epicardium ratio at 3.20.
Fig 4
Fig. 4
Cardiac magnetic resonance imaging (MRI) T2 sequence; short axis section of the left ventricular apex on situs inversus with evidence of large trabeculations (white arrow).
Fig 5
Fig. 5
Cardiac magnetic resonance imaging (MRI) T2 sequence; Four-cavity section (HLA); The endocardium/epicardium ratio is of more 3.80 than 2.3.
Fig 6
Fig. 6
T2 cardiac magnetic resonance imaging (MRI), short axis slice showing the apex of the left ventricle with numerous trabeculae (white arrow).
Fig 7
Fig. 7
Morphological classification of cardiomyopathies. A. Normal heart. B. Hypertrophic cardiomyopathy. C. Dilated cardiomyopathy. D. Arrhythmogenic right ventricular dysplasia. E. Restrictive cardiomyopathy: endocardial lines represent abnormal longitudinal fibers. F. Myocardial noncompaction: subendocardial layer has a trabecular structure with relative thinning of compacted outer myocardium .

References

    1. Engberding R., Bender F. Identification of a rare congenital anomaly of the myocardium by two-dimensional echocardiography: persistence of isolated myocardial sinusoids [archive] Am J Cardiol. 1984;53:1733–1734. - PubMed
    1. Paule P., Bream L., Mioulet D., Jop B., Théron A., Gril J.M., et al. Non-compaction of the left ventricle cardiomyopathy of the young subject: first African observations. Trop Med. 2007;67:587–593. - PubMed
    1. Varghese A., Pennel D.J. Elsevier Health Sciences; Amsterdam, Netherlands: 2007. Cardiovascular magnetic resonance made easy; p. 176. pages.
    1. Thavediranathan P., Cbow C.g. Proceedings of the new scientific lectures of the division of cardiology. volume XIII. St. Michael's Hospital. University of Toronto; 2008. Isolated ventricular noncompaction: a new cardiomyopathy.
    1. Diop A.D., Cassagne I., Alfidja A., Gageanu C., Diop A.N., Charbrot P., et al. Contribution of MRI in the diagnosis of left ventricular non-compaction: about two cases. J Afr Imag. 2014;6(3):50–55.

Publication types

LinkOut - more resources