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. 2022 Sep-Oct;85(5):506-512.
doi: 10.5935/0004-2749.20220074.

Epidemiological and clinical analyses of corneal transplants performed in a reference eye center in Recife, Brazil

Edilana Sá Ribeiro  1   2 , Anne Elizabeth Ferraz de Andrada  1 , Taciana Mirely Maciel Higino  3 , Isadora Diógenes Lopes  1 , Adriano Cabral de Vasconcelos  1 , Analine Lins de Medeiros  1 , Camilla Silva da Rocha  3 , Camila V Ventura  1   2   3
Affiliations

Epidemiological and clinical analyses of corneal transplants performed in a reference eye center in Recife, Brazil

Edilana Sá Ribeiro et al. Arq Bras Oftalmol. 2022 Sep-Oct.

Abstract
in English, Portuguese

Purpose: To evaluate the epidemiological and clinical profiles of corneal transplants performed in a reference eye center in Recife, state of Pernambuco, Northeastern Brazil.

Methods: This cross-sectional study collected epidemiological and clinical data from the medical records of patients who underwent keratoplasty at the Altino Ventura Foundation between January and December 2017.

Results: A total of 356 procedures were performed in 327 patients, of whom 165 (50.5%) were female. The mean age at surgery was 50.9 ± 22.6 years (range, 10-89 years). Most patients (n=152 [46.5%]) were from the capital and metropolitan areas. The mean waiting time for keratoplasty was 52.4 ± 58.9 days (range, 0-460 days). The main indications for keratoplasty were infectious keratitis (n=88 [24.7%]), keratoconus (n=80 [22.5%]), and previous transplant failure (n=75 [21.1%]). Penetrating keratoplasty was the most common surgical technique performed (n=213 [59.9%]) and more frequently performed in men (n=132 [76.7%]), whereas posterior lamellar transplant (n=143 [41.1%]) was more frequently performed in women (p<0.001).

Conclusion: Infectious keratitis was the main indication for keratoplasty, which was similarly performed in economically active adults of both sexes. Penetrating keratoplasty was more frequently performed in men and lamellar transplants in women.

Objetivo: Avaliar o perfil clínico e epidemiológico dos transplantes de córnea realizados em um centro de referência oftalmológica de Recife no estado de Pernambuco, localizado no nordeste do Brasil.

Métodos: Esse estudo transversal coletou através de prontuários médicos dados clínicos e epidemiológicos de pacientes submetidos a ceratoplastia na Fundação Altino Ventura, de janeiro a dezembro de 2017.

Resultados: Um total de 356 procedimentos foram realizados em 327 pacientes dos quais 165 (50.5%) eram mulheres. A média de idade na cirurgia foi de 50.9 ± 22.6 anos (variação, 10 - 89 anos). A maioria dos pacientes (n=152 [46.5%]) era da capital e região metropolitana. A média de tempo de espera na fila para o transplante de córnea foi de 52.4 ± 58.9 dias (variação, 0 - 460 dias). As principais indicações de transplante foram ceratite infecciosa (n=88 [24.7%]), ceratocone (n=80 [22.5%]) e falência de transplante prévio (n=75 [21.1%]). Transplante penetrante foi a técnica mais realizada (n=213 [59.9%]) e foi mais comum em homens (n=132 [76.7%]), enquanto os transplantes lamelares posteriores (n=143 [41.1%]) foram mais realizados nas mulheres (p<0.001).

Conclusão: Ceratites infecciosas foram a causa mais comum de transplante, com prevalência similar em adultos economicamente ativos de ambos os sexos. Transplante penetrantes foram os prevalentes em homens e os transplantes lamelares em mulheres.

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Conflict of interest statement

Disclosure of potential conflicts of interest: None of the authors have any potential conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Distribution of the main diagnoses according to sex.
Figure 2
Figure 2
Distribution of the main diagnoses according to age range.
Figure 3
Figure 3
Surgical techniques used according to age (n=356). The bars represent the total number of procedures (transplants and retransplants).
Figure 4
Figure 4
Surgical techniques used according to age group among (A) females (n=165) and (B) males (n=162). The bars represent the total number of procedures (transplants and retransplants).
Figure 5
Figure 5
Surgical techniques used according to transplant indication. The bars represent the percentages of the procedures performed.
See this image and copyright information in PMC

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