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. 2022 Apr 1;136(4):588-593.
doi: 10.1097/ALN.0000000000004143.

When Regional Anesthesia Met Pharmacokinetics

Laurence E Mather  1 , Geoffrey T Tucker  2
Affiliations

When Regional Anesthesia Met Pharmacokinetics

Laurence E Mather et al. Anesthesiology. .

Abstract

Pharmacokinetics of Local Anaesthetic Agents. By Tucker GT, Mather LE. Br J Anaesth 1975; 47(suppl 1):213-24 Information derived from measurements of blood concentrations of local anaesthetics can be extended by the application of pharmacokinetic analysis. A better understanding of quantitative aspects of the disposition and absorption of these drugs should assist the anaesthetist in deciding the optimal agent and dosage for regional block techniques.

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