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. 2022 Jan 15;14(1):355-363.
eCollection 2022.

Efficacy of thoracoscopy combined with laparoscopy and esophagectomy and analysis of the risk factors for postoperative infection

Junding Song  1 , Fujuan Chu  2 , Wenjie Zhou  3 , Yi Huang  1
Affiliations

Efficacy of thoracoscopy combined with laparoscopy and esophagectomy and analysis of the risk factors for postoperative infection

Junding Song et al. Am J Transl Res. .

Abstract

Objective: To explore the efficacy of thoracoscopy combined with laparoscopy (TCL) and esophagectomy in patients with esophageal carcinoma (EC) and analyze the risk factors for postoperative infection.

Methods: A total of 122 patients with EC admitted to our hospital were randomly divided into the study group (SG) and the control group (CG), with 61 patients in each group. Patients in the SG were treated with TCL, while patients in the CG were treated with traditional radical surgery for EC. The operation time, intraoperative blood loss, swallowing function, length of stay (LOS), number of lymph node dissections, postoperative infection rate, and quality of life in the first month after treatment were recorded and compared between the two groups. A logistic regression model was used to analyze the risk factors for postoperative infection.

Results: The operation time, intraoperative blood loss, LOS, and postoperative infection rate of the SG were significantly lower than those of the CG (all P<0.05). However, the number of lymph node dissections, swallowing function, and quality of life of patients in the SG were significantly higher than those in the CG, with statistically significant differences (all P<0.05). Postoperative hypoproteinemia, diabetes mellitus, and surgical mode were independent risk factors for postoperative infection in patients with EC (P<0.05).

Conclusion: Compared with traditional radical surgery for EC, TCL and resection can effectively reduce trauma, improve the lymph node dissection rate, promote postoperative recovery, and reduce postoperative infection, which is worthy of clinical application and promotion. Hypoproteinemia, diabetes mellitus, and surgical procedures are independent risk factors for postoperative infection in patients with EC. However, with improved medical technologies, the attention to and understanding of these high-risk factors can effectively improve postoperative infection in EC patients.

Keywords: Thoracoscopy combined with laparoscopy; postoperative infection; resection of esophageal carcinoma; risk factor.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Comparison of operative time and intraoperative blood loss between the two groups of patients. A. The operation time of SG was shorter than that of CG. B. The intraoperative blood loss of SG was lower than that of CG. Note: * indicates P<0.05.
Figure 2
Figure 2
Comparison of LOS and lymph node dissection between the two groups of patients. The LOS of SG was shorter than that of CG (A), and the number of lymph node dissection was greater than that of CG (B) (P<0.05). Note: * indicates P<0.05.
Figure 3
Figure 3
Comparison of swallowing function before and after treatment between the two groups of patients. There was no difference in swallowing function between the two groups before treatment (P>0.05). The swallowing function of the two groups was significantly improved after treatment, and the swallowing function of SG was better than that of CG (P<0.05). Note: * indicates P<0.05.
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