Sonoporation-Mediated Gene Transfection: A Novel Direction for Cell Reprogramming In Vivo

Meng Du^{1

2}, Yue Li^{1

2

3}, Zhiyi Chen^{1

2}

Affiliations

¹ The First Affiliated Hospital, Medical Imaging Centre, Hengyang Medical School, University of South China, Hengyang, China.
² Institute of Medical Imaging, Hengyang Medical School, University of South China, Hengyang, China.
³ Laboratory of Ultrasound Molecular Imaging, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

PMID: 35174147
PMCID: PMC8841490
DOI: 10.3389/fbioe.2021.803055

Sonoporation-Mediated Gene Transfection: A Novel Direction for Cell Reprogramming In Vivo

Meng Du et al. Front Bioeng Biotechnol. 2022.

. 2022 Jan 31:9:803055.

doi: 10.3389/fbioe.2021.803055. eCollection 2021.

Authors

Meng Du^{1

2}, Yue Li^{1

2

3}, Zhiyi Chen^{1

2}

Affiliations

¹ The First Affiliated Hospital, Medical Imaging Centre, Hengyang Medical School, University of South China, Hengyang, China.
² Institute of Medical Imaging, Hengyang Medical School, University of South China, Hengyang, China.
³ Laboratory of Ultrasound Molecular Imaging, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

PMID: 35174147
PMCID: PMC8841490
DOI: 10.3389/fbioe.2021.803055

No abstract available

Keywords: cell reprogramming; gene delivery; physical stimulation; regenerative medicine; ultrasound.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

1. Bez M., Kremen T. J., Tawackoli W., Avalos P., Sheyn D., Shapiro G., et al. (2018). Ultrasound-Mediated Gene Delivery Enhances Tendon Allograft Integration in Mini-Pig Ligament Reconstruction. Mol. Ther. 26 (7), 1746–1755. 10.1016/j.ymthe.2018.04.020 - DOI - PMC - PubMed
1. Carpentier A., Canney M., Vignot A., Reina V., Beccaria K., Horodyckid C., et al. (2016). Clinical Trial of Blood-Brain Barrier Disruption by Pulsed Ultrasound. Sci. Transl Med. 8 (343), 343re2. 10.1126/scitranslmed.aaf6086 - DOI - PubMed
1. Chong Z. X., Yeap S. K., Ho W. Y. (2021). Transfection Types, Methods and Strategies: A Technical Review. PeerJ 9, e11165. 10.7717/peerj.11165 - DOI - PMC - PubMed
1. Delalande A., Leduc C., Midoux P., Postema M., Pichon C. (2015). Efficient Gene Delivery by Sonoporation Is Associated with Microbubble Entry into Cells and the Clathrin-Dependent Endocytosis Pathway. Ultrasound Med. Biol. 41 (7), 1913–1926. 10.1016/j.ultrasmedbio.2015.03.010 - DOI - PubMed
1. Dimcevski G., Kotopoulis S., Bjånes T., Hoem D., Schjøtt J., Gjertsen B. T., et al. (2016). A Human Clinical Trial Using Ultrasound and Microbubbles to Enhance Gemcitabine Treatment of Inoperable Pancreatic Cancer. J. Control. Release 243, 172–181. 10.1016/j.jconrel.2016.10.007 - DOI - PubMed

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Sonoporation-Mediated Gene Transfection: A Novel Direction for Cell Reprogramming In Vivo

Affiliations

Sonoporation-Mediated Gene Transfection: A Novel Direction for Cell Reprogramming In Vivo

Authors

Affiliations

Conflict of interest statement

References

LinkOut - more resources

Full Text Sources